Complement /
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Book |
| Language: | English |
| Published: |
Oxford ; New York :
IRL Press at Oxford University Press,
[1995]
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| Edition: | Second edition. |
| Series: | In focus (Oxford, England)
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| Subjects: |
Table of Contents:
- Complement
- Introduction
- Nomenclature
- General outline of the complement system
- Activation and control of the complement system
- Activation of the classical pathway
- Central role of C3
- Activation of the alternative pathway
- Activation of C5
- Activation of membrane attack complex (MAC) C5b-9
- Control of the complement system
- C1-inhibitor (C1-Inh) and the C1 complex
- Anaphylatoxin inactivator
- Factor I and its cofactors and related regulatory proteins
- Regulation of the membrane attack complex
- The stabilizing role of properdin
- C1 activation
- Activation of the complement pathways
- Internal thiolester and covalent binding of C3
- Membrane attack complex
- Groups and families of proteins in the complement system
- C1q and related proteins
- C1q
- Mannan binding protein (MBP) and conglutinin.
- The serine proteases of the complement system
- C1r and C1s
- Mannan-binding protein-associated serine protease (MASP)
- Factor D
- Factor B and C2
- Factor I
- Complement genes in the class III region of the major hitocompatibility complex (MHC)
- C3, C4, and C5.
- Regulators of complement activation (RCA) and related proteins
- Components of the membrane attack complex (MAC)
- MAC inhibition factors
- Properdin
- Complement receptors and the integrins
- C5a receptor and G-protein complexes
- Molecular genetics of complement components
- C1q and related molecules
- MHC genetics and C4 polymorphism
- Thiolester proteins
- MAC components and MAC inhibitors
- Proteins of the RCA family
- C3 receptors
- Chemotactic receptors
- Role of the complement in health and disease
- Biosynthesis of complement components
- Immune complex clearance
- Inflammation
- Opsonization and phagocytosis
- Lytic function
- Interaction of complement with microorganisms
- Bacteria
- Parasites
- Viruses
- the role of complement in the immune response
- Complement deficiencies
- Clinical applications
- Biosynthesis of complement components
- Immune complex clearance
- Inflammation.
- Opsonization and phagocytosis
- Lytic function
- Complement and microorganisms
- Complement and the immune response
- Complement deficiencies
- Clinical applications.