DNA structure and recognition /
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Oxford, Eng. ; New York :
IRL Press at Oxford University Press,
[1994]
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| Edition: | First edition. |
| Series: | In focus (Oxford, England)
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| Subjects: |
Table of Contents:
- Methods for studying DNA structure
- X-ray diffraction methods for structural analysis
- NMR methods for studying DNA structure and dynamics
- Molecular modeling and simulation of DNA
- Chemical and enzymatic probes of structure
- Sources of structural data
- Building-blocks of DNA
- Base pairing
- Sugar puckers
- Conformations about the glycosidic bond
- Backbone torsion angles and correlated flexibility
- DNA structure as observed in fibres and crystals
- Structural fundamentals
- Helical parameters
- Morphological features of base pairs.
- Polynucleotide structures from fibre diffraction studies
- Classic DNA structures
- DNA polymorphism in fibres
- B-DNA oligonucleotide structure as seen in crystallographic analyses
- Dickerson-Drew duodecamer
- Sequence-dependent features
- Other B-DNA oligonucleotide structures
- A-DNA oligonucleotide crystal structures
- A-form octanucleotides
- A-form oligonucleotides in solution? Crystal packing effects
- Z-DNA left handed DNA
- Z-DNA hexanucleotide crystal structure
- Structural features
- Z-DNA helix
- Other Z-DNA structures.
- Biological aspects of Z-DNA
- Bent DNA
- DNA periodicity in solution
- Tracts and bending
- Structure of poly- and oligo(dA-dT)
- DNA-DNA recognition: non-standard DNA structures
- Mismatches in DNA
- General aspects
- Purine: purine mismatches
- Alkylation mismatches
- Multi-stranded DNA helices
- Triple helix
- Guanine quadruplexes
- Principles of ligand-DNA recognition
- DNA-water interactions
- DNA-drug recognition
- Non-covalent binding
- Covalent bonding
- Principles of protein-DNA recognition
- Major groove interactions-the α-helix as the recognition element.
- Zinc finger and other recognition modes
- Minor groove recognition
- DNA conformation and drug/protein recognition
- Detailed aspects of DNA structure.