DNA structure and recognition /

Bibliographic Details
Main Author: Neidle, Stephen
Format: Book
Language:English
Published: Oxford, Eng. ; New York : IRL Press at Oxford University Press, [1994]
Edition:First edition.
Series:In focus (Oxford, England)
Subjects:

MARC

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245 1 0 |a DNA structure and recognition /  |c Stephen Neidle. 
250 |a First edition. 
264 1 |a Oxford, Eng. ;  |a New York :  |b IRL Press at Oxford University Press,  |c [1994] 
264 4 |c ©1994 
300 |a ix, 108 pages :  |b illustrations (some color) ;  |c 23 cm. 
336 |a text  |2 rdacontent  |b txt 
337 |a unmediated  |2 rdamedia 
338 |a volume  |2 rdacarrier  |b nc 
490 1 |a In focus 
504 |a Includes bibliographical references and index. 
505 0 |a Methods for studying DNA structure -- X-ray diffraction methods for structural analysis -- NMR methods for studying DNA structure and dynamics -- Molecular modeling and simulation of DNA -- Chemical and enzymatic probes of structure -- Sources of structural data -- Building-blocks of DNA -- Base pairing -- Sugar puckers -- Conformations about the glycosidic bond -- Backbone torsion angles and correlated flexibility -- DNA structure as observed in fibres and crystals -- Structural fundamentals -- Helical parameters -- Morphological features of base pairs. 
505 0 |a Polynucleotide structures from fibre diffraction studies -- Classic DNA structures -- DNA polymorphism in fibres -- B-DNA oligonucleotide structure as seen in crystallographic analyses -- Dickerson-Drew duodecamer -- Sequence-dependent features -- Other B-DNA oligonucleotide structures -- A-DNA oligonucleotide crystal structures -- A-form octanucleotides -- A-form oligonucleotides in solution? Crystal packing effects -- Z-DNA left handed DNA -- Z-DNA hexanucleotide crystal structure -- Structural features -- Z-DNA helix -- Other Z-DNA structures. 
505 0 |a Biological aspects of Z-DNA -- Bent DNA -- DNA periodicity in solution -- Tracts and bending -- Structure of poly- and oligo(dA-dT) -- DNA-DNA recognition: non-standard DNA structures -- Mismatches in DNA -- General aspects -- Purine: purine mismatches -- Alkylation mismatches -- Multi-stranded DNA helices -- Triple helix -- Guanine quadruplexes -- Principles of ligand-DNA recognition -- DNA-water interactions -- DNA-drug recognition -- Non-covalent binding -- Covalent bonding -- Principles of protein-DNA recognition -- Major groove interactions-the α-helix as the recognition element. 
505 0 |a Zinc finger and other recognition modes -- Minor groove recognition -- DNA conformation and drug/protein recognition -- Detailed aspects of DNA structure. 
650 2 |a DNA Ligases  |x metabolism. 
650 2 |a DNA. 
830 0 |a In focus (Oxford, England) 
999 |a MARS 
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