Table of Contents:
  • Concepts and mechanisms
  • Methods and concepts in detecting abnormal reproductive outcomes of paternal origin
  • Laboratory device
  • Specific-locus mulation tests in germ cells of the mouse: an assessment of the screening procedures and the mutational events detected
  • Effects of spermatogenic cell type on quality of mutations
  • Dominant mutations in mice
  • Aneuploidy tests: cytogenetic analyses of mammalian male germ cells
  • Strategies for the use of a multiple-endpoint system for mammalian germ cell mutation testing
  • Transgenic mice in developmental toxicology.
  • Male mice receiving very low doses of ionizing radiation transmit an embryonic cell proliferation disadvantage to their progeny embryos
  • Post-testicular mechanisms of male-mediated developmental toxicity
  • Laboratory evidence for congenital anomalies, cancer and neurobehavioral outcomes
  • Male-mediated developmental toxicity of cyclophosphamide
  • Male-mediated teratogenesis: ionizing radiation/ethylnitrosourea studies
  • Preconception exposure of males and neoplasia in their progeny: effects of metals and consideration of mechanisms.
  • Male-mediated reproductive toxicity: effects on the nervous system of offspring
  • Epidemiologic findings
  • Paternal occupation and birth defects
  • Male-mediated developmental toxicity: paternal exposures and childhood cancer
  • Paternal exposures and pregnancy outcome: miscarriage, stillbirth, low birth weight, preterm delivery
  • Paternal exposures and embryonic or fetal loss: the toxicologic and epidemiologic evidence
  • Reproductive outcomes among men treated for cancer
  • Genetic effects of atomic bomb exposure.
  • Biological factors related to male mediated reproductive and developmental toxicity
  • Antioxidant prevention of birth defects and cancer
  • Risk assessment and policy issues
  • Quantitative risk assessment for paternally-mediated developmental toxicity
  • Paternally-mediated developmental toxicity: implications for risk assessment and science policy
  • Physician and patient education
  • Characteristics of male-mediated teratogenesis
  • Abstracts
  • Aneuploidy studies in sperm: post meiotic selection against aneuploid sperm.
  • Association of paternal and maternal exposure with low birth weight and preterm births among women textile workers
  • Genotoxic consequences of testicular localization of indium-114m
  • Male-mediated developmental and reproductive toxicity of Symm-Triazine pesticides
  • National transplantation pregnancy registry: outcomes of pregnancies fathered by male transplant recipients
  • Occupations of fathers before conception and the risk of testicular cancer in their sons
  • Two-dimensional electrophoresis of proteins: detection and characterization of male-mediated developmental toxicity.
  • Workshop report on mechanisms
  • Biomarkers and health endpoints of developmental toxicology of paternal origin
  • Epidemiological approaches
  • Laboratory research methods in male-mediated toxicity
  • Physician and patient education
  • Risk assessment and risk management
  • Multidisciplinary approaches.