Metabotropic glutamate receptors /
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Austin :
R.G. Landes Co.,
1994.
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| Series: | Medical intelligence unit.
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| Subjects: |
Table of Contents:
- Metabotropic glutamate receptor concept
- Identification of metabotropic glutamate receptors in the brain
- Stimulation of phosphoinositide hydrolysis
- Inhibition of phosphoinositide hydrolysis
- Intracellular Ca²⁺
- cAMP production
- Other responses
- Cloning and expression of metabotropic glutamate receptors
- Molecular structure
- Pharmacology, signal transduction and distribution of cloned receptor subtypes in the brain
- mGluR1α,† and c clones
- mGluR2 clone
- mGluR3 clone
- mGluR4 clone
- mGluR5 clone
- mGluR6 clone
- mGluR7 clone.
- Metabotropic receptor agonist effects on nerve cell physiology
- Frequency of neuronal discharges
- Action potential duration and afterdepolarization
- Membrane depolarization
- Afterhyperpolarization and Ca²⁺-dependent K⁺ current (Iahp)
- Synaptic transmission
- Synaptic plasticity.