Manipulating the mouse embryo : a laboratory manual /

Bibliographic Details
Other Authors: Hogan, Brigid
Format: Book
Language:English
Published: Plainview, N.Y. : Cold Spring Harbor Laboratory Press, 1994.
Edition:Second edition.
Subjects:
Table of Contents:
  • Developmental genetics and embryology of the mouse: past, present and future
  • Summary of mouse development
  • Setting up a colony for the production of transgenic and mutant mice
  • Recovery, culture and transfer of embryos and germ cells
  • In vitro manipulation of preimplantation embryos
  • Production of transgenic mice
  • Isolation, culture and manipulation of embryonic stem cells
  • Analysis of transgenic mice
  • Techniques for visualizing genes, gene products and specialized cell types
  • In vitro culture of eggs, embryos, primordial germ cells and teratocarcinoma cells
  • Buffers and solutions
  • Acidic tyrode solution for removing zonae
  • Alkaline phosphatase buffers
  • Alkaline phosphatase staining solution
  • Avertin, anesthetic
  • Bovine serum albumin (BSA)
  • Ca⁺⁺/Mg⁺⁺-free PBS
  • Ca⁺⁺/Mg⁺⁺-free tyrode ringer's saline (pH 7.6-7.7)
  • Hyaluronidase
  • NTM buffer (NTMT without tween 20) for in situ hybridization of intact embryos with RNA probes
  • NTMT buffer for in situ hybridization of intact embryos with RNA probes
  • Pancreatin/trypsin solution for separating germ and tissue layers
  • PBSMT for immunohistochemistry of whole mount embryos
  • PBT
  • Phenol/chloroform solution for isolating total RNA from mouse embryos or fetal tissues
  • Phosphate-buffered saline (PBS ̲-- Pronase solution
  • Saline/EDTA buffer plus glucose for isolation of germ cells and tissue culture
  • 20X SSC
  • 20X SSPE
  • TE (tris/EDTA) buffer
  • 0.25% trypsin in tris-saline for tissue culture
  • Trypsin/EDTA solutions
  • Sources of information
  • Genetic resources
  • Books
  • Journals
  • Databases
  • Software
  • Suppliers
  • Inbred, hybrid and random-bred mice
  • Mouse genomic DNAs and RNAs
  • Mouse genomic and cDNA libraries and clones
  • Equipment and supplies