Molecular endocrinology : basic concepts and clinical correlations /
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| Format: | Book |
| Language: | English |
| Published: |
New York :
Raven Press,
[1995]
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| Subjects: |
Table of Contents:
- Basic concepts and techniques in molecular biology
- Diverse mechanisms for regulation of hormone synthesis and action: relationship to endocrine diseases and the human genome project
- DNA sequence analysis
- Linkage analysis of human diseases
- Localizing mutations in human genes
- Measurement of gene transcription and messenger RNA
- Transcriptional regulation of endocrine genes by second-messenger signaling pathways
- Transgenic mice provide multiple paradigms for studies in molecular endocrinology.
- Gene targeting by homologous recombination in mouse embryonic stem cells
- Hormone and receptor genes
- Cloning and expression of polypeptide hormone genes
- Cloning and regulation of catecholamine receptor genes
- Cloning and regulation of glycoprotein hormone receptor genes
- Non-receptor-binding proteins for insulin-like growth factors and other cytokines: modulators of peptide action
- Molecular and cellular biology of the insulin-like growth factors
- Steroid hormone receptor superfamily: molecular mechanisms of action.
- Thyroid hormone response elements
- Posttranscriptional effects of thyroid hormones
- Integrated view of thyroid hormone actions in vivo
- Endocrine diseases
- Type I diabetes mellitus
- Mutations in the insulin receptor gene in insulin resistant patients
- G protein dysfunction in disease
- Graves' disease and autoimmune thyroiditis
- Genetic abnormalities of thyroid hormone transport serum proteins
- Molecular basis of hypogonadotropic hypogonadism
- Thyroid hormone resistance
- Mutations in the androgen receptor gene that cause androgen resistance.
- Vitamin D resistance
- Molecular aspects of familial glucocorticoid resistance
- Congenital adrenal hyperplasia
- Growth hormone deficiency
- Endocrine therapy with recombinant hormones and growth factors.