Drug design for neuroscience /

Bibliographic Details
Other Authors:	Kozikowski, Alan P.
Format:	Book
Language:	English
Published:	New York : Raven Press, [1993]
Subjects:	Brain Diseases > drug therapy. Drug Design. Receptors, Cell Surface > antagonists & inhibitors. Receptors, Cell Surface > drug effects.

Table of Contents:

Neurotransmitter receptors as pharmacological targets in Alzheimer's disease: design of drugs on a rational basis / Povl Krogsgaard-Larsen
Design and synthesis of BMY 21502: a potential memory and cognition enhancing agent / Ronald J. Mattson and Joseph P. Yevich
Muscarinic agonists for the central nervous system / Raymond Baker and Angus M. MacLeod
Novel organic reactions in the search for anxioselective anxiolytics at the benzodiazepine receptor / Weijiang Zhang and James M. Cook
Design of orally active dopamine autoreceptor agonists / Lawrence D. Wise and Juan C. Jaen
3†-(substituted phenyl)tropan-2-carboxylic acid ester analogues of cocaine: synthesis and biochemical and pharmacological properties / F. Ivy Carroll ... [et al.]
Serotonin receptors, agents, and actions / Jeffrey L. Herndon and Richard A. Glennon
Studies of a novel series of thiazole-containing 5-hydroxytryptamine-3 receptor antagonists / Terry Rosen, Arthur A. Nagel and James P. Rizzi.
(cont) Conformationally constrained acidic amino acids as probes of glutamate receptors and transporters / Richard Chamberlin and Richard Bridges
L-2-(carboxycyclopropyl)glycines: conformationally constrained L-glutamate analogues / Yasufumi Ohfune and Haruhiko Shinozaki
Design and synthesis of conformationally constrained acidic amino acids as N-methyl-D-aspartic acid receptor antagonists / Paul L. Ornstein
Modulation of the N-methyl-D-aspartate (NMDA) receptor complex: design and synthesis of competitive NMDA antagonists and phencyclidine (PCP)-site ligands / Christopher F. Bigge ... [et al.]
Glycine-site N-methyl-D-aspartate receptor antagonists / Paul D. Leeson
Synthetic inositol polyphosphates and analogues as molecular probes for neuronal second messenger receptors / Barry V.L. Potter and Stefan R. Nahorski
Inositol 1,4,5-triphosphate affinity chromatography: fishing out novel ins(1,4,5)P₃-recognizable proteins / Shoichiro Ozaki ... [et al.]
Chemical approaches to brain-targeting of biologically active compounds / Marcus E. Brewster, Emil Pop and Nicholas Bodor.