rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Health risk assessment
    sub title: dermal and inhalation exposure and absorption of toxicants
  name:
    name part: Wang, Rhoda G. M.
    name part: 1947-
  name:
    name part: Knaak, James B.
  name:
    name part: Maibach, Howard I.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: flu
    date issued: 1993
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: 527 pages : illustrations, map ; 27 cm.
  table of contents: Physiologically based pharmacokinetic modeling to predict tissue dose and cholinesterase inhibition in workers exposed to organophosphorus and carbamate pesticides -- Application of pharmacokinetic mosels to predict target dose -- Cytochrome P450-dependent metabolism of drugs and carcinogens in skin -- Percutaneous absorption -- In vitro skin metabolism -- Animal models for percutaneous absorption -- Comparative study of the kinetics and bioavailability of pure and soil-absorbed benzene, toluene, and m-xylene after dermal exposure -- Prediction of human percutaneous absorption with physicochemical data -- Dermal absorption of TCDD: effect of age.
  table of contents: (cont) Percutaneous absorption of chemicals from water during swimming and bathing -- Percutaneous absorption of contaminants from soil -- General overview on toxicological responses and routes of chemical exposure -- Acute toxicity testing by the dermal route -- Subchronic dermal exposure studies with industrial chemicals -- Dose response of percutaneous absorption -- Reproductive and developmental toxicity studies by cutaneous administration -- Dermal carcinogenicity studies of petroleum-derived materials -- Comparison of results from carcinogenicity tests of two halogenated compounds by oral, dermal, and inhalation routes -- Objectives and goals of dermal carcinogenicity testing of petroleum liquids.
  table of contents: (cont) Chemical carcinogenesis in skin: causation, mechanism, and role of oncogenes -- Incorporating biological information into the assessment of cancer risk to humans under various exposure conditions and issues related to high background tumor incidence rates -- Phototoxicity of topical and systemic agents -- Techniques for assessing the health risks of dermal contact with chemicals in the environment -- Interspecies extrapolation of toxicological data -- Human skin xenografts to athymic rodents as a system to study toxins delivered to or through the skin -- Isolated perfused porcine skin flap -- Perspectives on assessment of risk from dermal exposure to polycyclic aromatic hydrocarbons -- Paradox of herbicide 2,4-D epidemiology -- Review of epidemiologic studies with regard to routes of exposure to toxicants.
  note: edited by Rhoda G.M. Wang, James B. Knaak, Howard I. Maibach.
  note: Includes bibliographical references and index.
  subject:
    topic: Air Pollutants
    topic: toxicity
  subject:
    topic: Dose-Response Relationship, Drug
  subject:
    topic: Environmental Pollutants
    topic: toxicity
  subject:
    topic: Risk Factors
  subject:
    topic: Skin Absorption
  subject:
    topic: Toxicology
    topic: methods
  classification: RL803 .H43 1993
  classification: 616.5
  classification: QV 602 H434 (P)
  related item:
    title info:
      title: CRC series in dermatology
  identifier: 0849373573 (acid-free paper)
  identifier: 92020111
  record info:
    record content source: DNLM/DLC
    record creation date: 920521
    record change date: 20191202143646.0
    record identifier: in00004479291