PCR : clinical diagnostics and research /

Bibliographic Details
Format: Book
Language:English
Published: Berlin ; New York : Springer-Verlag, [1992]
Series:Springer laboratory.
Subjects:
Table of Contents:
  • PCR: principles and reaction components
  • Optimization strategies
  • General applications of PCR
  • Substances affecting PCR: inhibition or enhancement
  • PCR: contamination and falsely interpreted results
  • Biological material amenable to PCR
  • Isolation of DNA from cells and tissue for PCR
  • Isolation of RNA from cells and tissue for PCR
  • Reverse transcription/PCR (RT-PCR)
  • Methods for identification of amplified PCR products
  • Restriction fragment analysis
  • Multiplex PCR
  • Detection of single base changes using PCR
  • Non-radioactive, direct, solid-phase sequencing of genomic DNA obtained from PCR
  • Application of PCR to analyze unknown sequences
  • Quantification of PCR-products
  • Cloning methods using PCR
  • Site-directed mutagenesis using the PCR
  • In-situ polymerase chain reaction
  • Oligonucleotides in the field of PCR
  • Review of different heat-stable DNA polymerases
  • Physical features of thermocyclers and of their influence on the efficiency of PCR amplification
  • Alternative methods to PCR.