Gene amplification in mammalian cells : a comprehensive guide /

Bibliographic Details
Other Authors: Kellems, Rodney E., 1947-
Format: Book
Language:English
Published: New York : M. Dekker, [1993]
Subjects:
Table of Contents:
  • Cytogenetic consequences of gene amplification: HSRs and DMs in antifolate-resistant and multidrug-resistant Chinese hamster and mouse cells and in human neuroblastoma cells with amplified N-myc protooncogenes
  • Organization and stucture of dihydrofolate reductase amplicons
  • Analysis of gene amplification by in-gel DNA renaturation
  • Molecular cytogenetic characterization of the sequential development of multidrug resistance in two panels of colchicine-resistant cell lines
  • Effects of methotrexate on recombinant sequences in mammalian cells
  • Threnoyl-tRNA synthetase gene amplification in Borrelidin-resistant mammalian cells
  • Amplification of Na,K-ATPase in ouabain-resistant HeLa variants
  • Asparagine synthetase gene amplification in albizziin-resistant hamster and human cell lines
  • Overproduction of damage recognition proteins in human cells resistant to cisplatin and ultraviolet radiation
  • Ornithine decarboxylase gene amplification
  • Amplification of the IMP dehydrogenase gene in mammalian cells
  • Amplification and analysis of the mouse dihydrofolate reductase gene
  • Amplification of the adenylate-deaminase 2 and linked genes in Chinese hamster lung fibroblasts
  • Organization and amplification of metallothionein genes in eukaryotic cells
  • Thymidylate synthetase gene amplification in drug-resistant mammalian cells
  • Adenosine deaminase: a dominant amplifiable genetic marker
  • Amplification of the HPRT gene
  • Amplification of the gene for N-acetylglucosaminyl phosphate transferase, an enzyme catalyzing an early step in Asn-linked glycosylation, in Chinese hamster ovary cells resistant to tunicamycin
  • Amplification of CAD genes
  • Reversible selection system for UMP synthase gene amplification and deamplification
  • Amplification of the genes encoding the R1 and R2 subunits of mammalian ribonucleotide reductase
  • DNA amplification in histidinol-resistant Chinese hamster ovary cells
  • Amplification of the P-glycoprotein gene family and multidrug resistance
  • Glutamine synthetase gene amplification in Chinese hamster ovary cells
  • Amplification and expression of transfected genes in mammalian cells
  • Consequences of coamplification of adenosine deaminase and nonselected genes in a heterodiploid host
  • Production of proteins by mammalian cells using dominant selectable and amplifiable markers
  • Oncogene amplification: analysis of myc oncoproteins
  • Biological and clinical significance of MYCN amplification in human neuroblastomas
  • Amplification of the c-abl oncogene in chronic myelogenous leukemia
  • Gene amplification in small cell carcinoma of the lung
  • Amplification and mutagenesis of the acetylcholinesterase and butyrylcholinesterase genes in primary human tumors
  • Gene amplification in nontumorigenic and tumorigenic mammalian cells: relationship to carcinogenesis
  • Mechanisms of arsenic-induced gene amplification
  • Involvement of inverted duplications in the generation of gene amplification in mammalian cells
  • Genetics of amplification
  • "U-turn" replication at arrested forks leads to the generation of extrachromosomal inverted repeats
  • Stimulation of gene amplification in mammalian cells by HSAG middle repetitive elements
  • Amplisomes: novel submicroscopic extrachromosomal elements containing amplified genes
  • Cytogenetic and molecular dynamics of mammalian gene amplification: evidence supporting chromosome breakage as an initiating event.