Protocols in molecular parasitology /

Bibliographic Details
Other Authors: Hyde, John E.
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [1993]
Series:Methods in molecular biology (Clifton, N.J.) ; v. 21.
Subjects:
Table of Contents:
  • Culturing and biological cloning of Trypanosoma brucei
  • Culturing and biological cloning of Trypanosoma cruzi
  • In vitro cultivation and biological cloning of Leishmania
  • Simple in vitro cultivation of the malaria parasite Plasmodium falciparum (erythrocytic stages) suitable for large-scale preparations
  • Synchronization and cloning of malaria parasites
  • Culture and preparation of gametocytes of Plasmodium falciparum for immunochemical, molecular, and mosquito infectivity studies
  • Culture of Schistosoma mansoni and production of life cycle stages
  • Preparation of DNA and RNA from Trypanosoma brucei
  • Isolation of RNA and DNA from Trypanosoma cruzi
  • Isolation of DNA and RNA from Leishmania
  • Extraction and purification of DNA and RNA from in vitro cultures of the malaria parasite Plasmodium falciparum
  • Extraction and purification of nucleic acids from schistosomes
  • Application of DNA and whole organisms to filter supports for DNA probe analysis: dot, slot, and touch blotting
  • Development and use of repetitive sequences as DNA probes for parasite detection and species identification
  • Analysis of the DNA of parasitic protozoa by flow cytometry
  • PCR for low-level detection of malaria parasites in blood
  • PCR methods for identification of point mutations and gene rearrangements
  • Antigenic typing of field isolates of Plasmodium by DNA techniques
  • Ribosomal RNA probes for detection and identification of species
  • Rapid sequencing of parasite rRNA
  • Antibody screening of expression libraries
  • Antibody select procedure for characterization of expression clones
  • Isolation of parasite genes using synthetic oligonucleotides
  • Chromosome mapping methods for parasitic protozoa
  • Transfection of Leishmania and Trypanosoma brucei by electroporation
  • Two-dimensional polyacrylamide gel electrophoresis
  • Isoenzyme electrophoresis for parasite characterization
  • Surface labeling of schistosomes
  • Monclonal antibody affinity chromotography
  • Immunoblotting and enzyme linked immunosorbent assay
  • Immunofluorescence of parasites
  • Immunoelectron microscopic localization of antigens in malaria parasites
  • Preparation of blotted membrane for protein microsequencing
  • Identification of T-cell epitopes