Current concepts of a new animal model : the NON mouse /

Bibliographic Details
Other Authors: Sakamoto, N. (Nobuo), 1931-, Hotta, N., Uchida, K. (Kiyohisa)
Format: Book
Language:English
Published: Amsterdam ; New York : Elsevier, 1992.
Subjects:
Table of Contents:
  • Breeding of the NON mouse and its genetic characteristics
  • Biological characteristics of the NOD mouse, a related strain of the NON mouse
  • Analysis of the insulin genes in the NON mouse
  • Diabetic syndrome in the NON mouse
  • Body fat accumulation and metabolic disturbance in the NON mouse
  • Cytoplasmic Ca²⁺ response in pancreatic β cells of the NON mouse
  • Changes of the K⁺ channel of the pancreatic B cell in the NON mouse
  • Lipoproteins, cholesterol and bile acids in the NON mouse
  • Intranuclear filaments in the pancreatic B cells and abnormal glucose tolerance in the NON mouse
  • Histopathological observation of the development of glomerular intracapillary deposits in the NON mouse
  • Cell infiltration in various organs and dilatation of the urinary tubule in the NON mouse
  • Immunopathological observations of nephropathy and characterization of infiltrated lymphocytes
  • Renal pathological findings and abnormal GTT
  • Renal lesions and urinary bladder carcinogenesis