Nucleic acid targeted drug design /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York :
M. Dekker,
[1992]
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| Subjects: |
Table of Contents:
- Designing drugs that interact with nucleic acids / Thomas J. Perun and C.L. Propst
- Structural studies of drug-DNA interactions by x-ray crystallography and NMR spectroscopy / Andrew H.-J. Wang and Howard Robinson
- Modeling drug-nucleic acid interactions: an exercise in computer graphics and computational chemistry / Shashidhar N. Rao
- Sequence specificity of drug-DNA interactions / James C. Dabrowiak, Allison A. Stankus and Jerry Goodisman
- Construction of quantitative structure-activity relationships (QSARs) from ligand-DNA molecular modeling studies / A.J. Hopfinger, Mario Gustavo Cardozo and Yoshiyuki Kawakami
- Molecular basis of sequence-specific DNA-protein interactions / Thomas Kodadek
- Netropsin and the lexitropsins: the search for sequence-specific minor-groove-binding ligands / Mary L. Kopka and Teresa A. Larsen
- Pyrrolo(1,4)benzodiazepines: unraveling the complexity of the structures of the tomaymycin-DNA adducts in various sequences using fluorescence, 1H-NMR, and molecular modeling / William A. Remers, Mary D. Barkley and Laurence H. Hurley.
- (cont) Cooperative quinolone-DNA binding model for DNA gyrase inhibition: implications in drug design / Lester A. Mitscher and Linus L. Shen
- Mechanism of DNA damage by neocarzinostatin and other bicyclic enediyne antibiotics / Peter C. Dedon and Irving H. Goldberg
- Comparative studies of intercalative DNA-drug interactions using molecular modeling and biophysical techniques / Mavis Agbandje and Robert McKenna
- Catalytic antisense RNAs: principles and design / James O. Deshler and John J. Rossi
- Oligonucleiotide-based therapeutics / Norbert Bischofberger and Regan G. Shea.