rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Nucleic acid targeted drug design
  name:
    name part: Propst, C. L. (Catherine Lamb)
    name part: 1946-
  name:
    name part: Perun, Thomas J.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: nyu
    date issued: 1992
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: xiii, 619 pages, 4 unnumbered pages of plates : illustrations (some color) ; 24 cm.
  table of contents: Designing drugs that interact with nucleic acids / Thomas J. Perun and C.L. Propst -- Structural studies of drug-DNA interactions by x-ray crystallography and NMR spectroscopy / Andrew H.-J. Wang and Howard Robinson -- Modeling drug-nucleic acid interactions: an exercise in computer graphics and computational chemistry / Shashidhar N. Rao -- Sequence specificity of drug-DNA interactions / James C. Dabrowiak, Allison A. Stankus and Jerry Goodisman -- Construction of quantitative structure-activity relationships (QSARs) from ligand-DNA molecular modeling studies / A.J. Hopfinger, Mario Gustavo Cardozo and Yoshiyuki Kawakami -- Molecular basis of sequence-specific DNA-protein interactions / Thomas Kodadek -- Netropsin and the lexitropsins: the search for sequence-specific minor-groove-binding ligands / Mary L. Kopka and Teresa A. Larsen -- Pyrrolo(1,4)benzodiazepines: unraveling the complexity of the structures of the tomaymycin-DNA adducts in various sequences using fluorescence, 1H-NMR, and molecular modeling / William A. Remers, Mary D. Barkley and Laurence H. Hurley.
  table of contents: (cont) Cooperative quinolone-DNA binding model for DNA gyrase inhibition: implications in drug design / Lester A. Mitscher and Linus L. Shen -- Mechanism of DNA damage by neocarzinostatin and other bicyclic enediyne antibiotics / Peter C. Dedon and Irving H. Goldberg -- Comparative studies of intercalative DNA-drug interactions using molecular modeling and biophysical techniques / Mavis Agbandje and Robert McKenna -- Catalytic antisense RNAs: principles and design / James O. Deshler and John J. Rossi -- Oligonucleiotide-based therapeutics / Norbert Bischofberger and Regan G. Shea.
  note: edited by C.L. Propst, Thomas J. Perun.
  note: Includes bibliographical references and index.
  subject:
    topic: DNA
    topic: pharmacology
  subject:
    topic: Drug Design
  classification: RS420 .N83 1992
  classification: 615/.19
  identifier: 0824786629
  identifier: 92017585
  record info:
    record content source: DLC
    record creation date: 920508
    record change date: 20191202143520.0
    record identifier: in00004477976