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| LEADER |
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920508s1992 nyuaf b 001 0 eng |
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|a 0824786629
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|a (OCoLC)25915133
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| 096 |
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|a QU 58
|b N9642 1992
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| 245 |
0 |
0 |
|a Nucleic acid targeted drug design /
|c edited by C.L. Propst, Thomas J. Perun.
|
| 264 |
|
1 |
|a New York :
|b M. Dekker,
|c [1992]
|
| 264 |
|
4 |
|c ©1992
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| 300 |
|
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|a xiii, 619 pages, 4 unnumbered pages of plates :
|b illustrations (some color) ;
|c 24 cm.
|
| 336 |
|
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|a text
|2 rdacontent
|b txt
|
| 337 |
|
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|a unmediated
|2 rdamedia
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| 338 |
|
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|a volume
|2 rdacarrier
|b nc
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| 504 |
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|a Includes bibliographical references and index.
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| 505 |
0 |
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|a Designing drugs that interact with nucleic acids / Thomas J. Perun and C.L. Propst -- Structural studies of drug-DNA interactions by x-ray crystallography and NMR spectroscopy / Andrew H.-J. Wang and Howard Robinson -- Modeling drug-nucleic acid interactions: an exercise in computer graphics and computational chemistry / Shashidhar N. Rao -- Sequence specificity of drug-DNA interactions / James C. Dabrowiak, Allison A. Stankus and Jerry Goodisman -- Construction of quantitative structure-activity relationships (QSARs) from ligand-DNA molecular modeling studies / A.J. Hopfinger, Mario Gustavo Cardozo and Yoshiyuki Kawakami -- Molecular basis of sequence-specific DNA-protein interactions / Thomas Kodadek -- Netropsin and the lexitropsins: the search for sequence-specific minor-groove-binding ligands / Mary L. Kopka and Teresa A. Larsen -- Pyrrolo(1,4)benzodiazepines: unraveling the complexity of the structures of the tomaymycin-DNA adducts in various sequences using fluorescence, 1H-NMR, and molecular modeling / William A. Remers, Mary D. Barkley and Laurence H. Hurley.
|
| 505 |
0 |
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|a (cont) Cooperative quinolone-DNA binding model for DNA gyrase inhibition: implications in drug design / Lester A. Mitscher and Linus L. Shen -- Mechanism of DNA damage by neocarzinostatin and other bicyclic enediyne antibiotics / Peter C. Dedon and Irving H. Goldberg -- Comparative studies of intercalative DNA-drug interactions using molecular modeling and biophysical techniques / Mavis Agbandje and Robert McKenna -- Catalytic antisense RNAs: principles and design / James O. Deshler and John J. Rossi -- Oligonucleiotide-based therapeutics / Norbert Bischofberger and Regan G. Shea.
|
| 650 |
|
2 |
|a DNA
|x pharmacology.
|
| 650 |
|
2 |
|a Drug Design.
|
| 700 |
1 |
|
|a Propst, C. L.
|q (Catherine Lamb),
|d 1946-
|
| 700 |
1 |
|
|a Perun, Thomas J.
|
| 999 |
|
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|a MARS
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| 999 |
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| 952 |
f |
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|p ric
|a Texas A&M University
|b Rellis Campus
|c Joint Library Facility
|d Remote Storage
|t 0
|e QU 58 N9642 1992
|h National Library of Medicine classification
|i unmediated -- volume
|m 3238901139398
|
| 998 |
f |
f |
|a QU 58 N9642 1992
|t 0
|l Remote Storage
|