Single-cell Sequencing and Methylation : Methods and Clinical Applications /
With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a...
| Corporate Author: | |
|---|---|
| Other Authors: | , , , , |
| Format: | eBook |
| Language: | English |
| Published: |
Singapore :
Springer Singapore : Imprint: Springer,
2020.
|
| Edition: | 1st ed. 2020. |
| Series: | Advances in Experimental Medicine and Biology,
1255 |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients. |
|---|---|
| Physical Description: | 1 online resource (VIII, 247 pages 117 illustrations, 114 illustrations in color.) |
| ISBN: | 9789811544941 |
| ISSN: | 2214-8019 ; |
| DOI: | 10.1007/978-981-15-4494-1 |