Table of Contents:
  • Introduction / Prasad, A. Krishna / http://dx.doi.org/10.1021/bk-2018-1290.ch001
  • Glycoconjugate Vaccines: The Clinical Journey / Lockhart, Stephen P., Pfizer Vaccines Clinical Research and Development, Horizon Building, Honey Lane, Hurley SL6 6RJ, United Kingdom; Scott, Daniel A., Pfizer Vaccine Clinical Research and Development, 500 Arcola Rd., Collegeville, Pennsylvania 19426, United States; Jansen, Kathrin U., Pfizer Vaccines Research and Development, 401 N. Middletown Rd., Pearl River, New York 10965-1299, United States; Anderson, Annaliesa S., Pfizer Vaccines Research and Development, 401 N. Middletown Rd., Pearl River, New York 10965-1299, United States; Gruber, William C., Pfizer Vaccines Research and Development, 401 N. Middletown Rd., Pearl River, New York 10965-1299, United States / http://dx.doi.org/10.1021/bk-2018-1290.ch002
  • Immunological Mechanisms of Glycoconjugate Vaccines / Duke, Jeremy A.; Avci, Fikri Y. / http://dx.doi.org/10.1021/bk-2018-1290.ch003
  • Design and Development of Glycoconjugate Vaccines / Prasad, A. Krishna; Kim, Jin-hwan; Gu, Jianxin / http://dx.doi.org/10.1021/bk-2018-1290.ch004
  • Manufacturing Considerations for Glycoconjugate Vaccines / Prasad, A. Krishna, Pfizer Vaccines Research and Development, 401 N. Middletown Rd., Pearl River, New York 10965, United States; Murphy, Kent, Pfizer Global Supply, 4300 Oak Park, Sanford, North Carolina 27330, United States; Kolodziej, Stephen A., Pfizer Biotherapeutics and Pharmaceutical Sciences, 700 Chesterfiled Parkway W., Chesterfield, Missouri 63017, United States / http://dx.doi.org/10.1021/bk-2018-1290.ch005
  • Multivalent Meningococcal Conjugate Vaccines: Chemical Conjugation Strategies Used for the Preparation of Vaccines Licensed or in Clinical Trials / Berti, Francesco / http://dx.doi.org/10.1021/bk-2018-1290.ch006
  • The Role of Molecular Modeling in Predicting Carbohydrate Antigen Conformation and Understanding Vaccine Immunogenicity / Kuttel, Michelle M., Department of Computer Science, University of Cape Town, Private Bag X3, Rondebosch 7701, Cape Town, South Africa; Ravenscroft, Neil, Department of Computer Science, University of Cape Town, Private Bag X3, Rondebosch 7701, Cape Town, South Africa / http://dx.doi.org/10.1021/bk-2018-1290.ch007
  • Advances in Synthetic Approaches towards Glycoantigens / Vartak, A. R.; Sucheck, S. J. / http://dx.doi.org/10.1021/bk-2018-1290.ch008
  • Formulation Development of Glycoconjugate Vaccines for Low- and Middle-Income Countries / Khandke, Lakshmi; Welsch, Jo Anne; Alderson, Mark R. / http://dx.doi.org/10.1021/bk-2018-1290.ch009
  • Preclinical Assessment of Glycoconjugate Vaccines / Scully, Ingrid L.; Swanson, Kena A.; Kanevsky, Isis; Prasad, A. Krishna; Anderson, Annaliesa S. / http://dx.doi.org/10.1021/bk-2018-1290.ch010
  • Campylobacter jejuni Capsule Polysaccharide Conjugate Vaccine / Monteiro, Mario A., Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Noll, Alexander, Enteric Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910, United States; Laird, Renee M., Enteric Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910, United States; Pequegnat, Brittany, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Ma, Zuchao, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Bertolo, Lisa, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; DePass, Christina, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Omari, Eman, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Gabryelski, Pawel, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Redkyna, Olena, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Jiao, Yuening, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Borrelli, Silvia, Department of Chemistry, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Poly, Frederic, Enteric Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910, United States; Guerry, Patricia, Enteric Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910, United States / http://dx.doi.org/10.1021/bk-2018-1290.ch011
  • Chemistry Manufacturing, Control, and Licensure for Carbohydrate-Based Vaccines / Jones, Christopher / http://dx.doi.org/10.1021/bk-2018-1290.ch012
  • Lessons Learned and Future Challenges in the Design and Manufacture of Glycoconjugate Vaccines / Hennessey, John P., Consultant, Lower Gwynedd, Pennsylvania 19002, United States; Costantino, Paolo, GSK, Siena 53100, Italy; Talaga, Philippe, Department of Analytical Research and Development, Sanofi Pasteur, Marcy l’Etoile 69280, France; Beurret, Michel, Janssen Vaccines & Prevention B.V., Leiden, 2301 CA, The Netherlands; Ravenscroft, Neil, Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Alderson, Mark R., PATH, Seattle, Washington 98121, United States; Zablackis, Earl, Analytical Process Technology, Sanofi Pasteur, Swiftwater, Pennsylvania 18370, United States; Prasad, A. Krishna, Pfizer Vaccines Research and Development, Pearl River, New York 10965, United States; Frasch, Carl, Consultant, Martinsburg, West Virginia 25402, United States / http://dx.doi.org/10.1021/bk-2018-1290.ch013
  • Editor’s Biography / http://dx.doi.org/10.1021/bk-2018-1290.ot001