In Silico Dreams : How Artificial Intelligence and Biotechnology Will Create the Medicines of the Future.
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| Format: | eBook |
| Language: | English |
| Published: |
Newark :
John Wiley & Sons, Incorporated,
2021.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Cover
- Title Page
- Copyright Page
- About the Author
- About the Technical Editor
- Acknowledgments
- Contents at a Glance
- Contents
- Introduction
- What Does This Book Cover?
- Reader Support for This Book
- Chapter 1 The Information Revolution's Impact on Biology
- A Biological Data Avalanche at Warp Speed
- Tracking SARS-CoV-2 with Genomic Epidemiology
- Biology's Paradigm Shift Enables In Silico Biology
- Transitions and Computation in Cancer Research
- Structural Biology and Genomics
- Sequencing the Human Genome
- Computational Biology in the Twenty-First Century
- Applications of Human Genome Sequencing
- Analyzing Human Genome Sequence Information
- Omics Technologies and Systems Biology
- Notes
- Chapter 2 A New Era of Artificial Intelligence
- AI Steps Out of the Bronx
- From Neurons and Cats Brains to Neural Networks
- Machine Learning and the Deep Learning Breakthrough
- Deep Learning Arrives for AI
- Deep Neural Network Architectures
- Deep Learning's Beachhead on Medicine: Medical Imaging
- Limitations on Artificial Intelligence
- Notes
- Recommended Reading
- Chapter 3 The Long Road to New Medicines
- Medicine's Origins: The Role of Opium Since the Stone Age
- Industrial Manufacturing of Medicines
- Paul Ehrlich and the Birth of Chemotherapeutic Drug Discovery
- The Pharmaceutical Industry: Drugs and War-New Medicines in the Twentieth Century
- From Synthetic Antibiotics to the Search for New Drugs from the Microbial World
- Developing Therapeutics for Cancer
- Antifolates and the Emergence of DNA Synthesis Inhibitors
- Antibiotics as Cancer Chemotherapeutic Drugs
- Immunotherapy
- The Pharmaceutical Business Model in the Twenty-First Century
- R&D Productivity Challenges Within the Pharmaceutical Industry
- Sources of Pharmaceutical Innovation: Biotechnology and New Therapeutic Modalities
- Notes
- Recommended Reading
- Chapter 4 Gene Editing and the New Tools of Biotechnology
- Molecular Biology and Biological Information Flow
- Manipulating Gene Information with Recombinant DNA Technology
- Genetics, Gene Discovery, and Drugs for Rare Human Diseases
- Second-Generation Biotechnology Tools: CRISPR- Cas9 and Genome Editing Technologies
- Human Genome Editing and Clinical Trials
- Biotechnology to the Rescue: Vaccine Development Platforms Based on Messenger RNA
- Recommended Reading
- Notes
- Chapter 5 Healthcare and the Entrance of the Technology Titans
- Digital Health and the New Healthcare Investment Arena
- Assessing the Tech Titans as Disruptors in Healthcare
- Alphabet: Extending Its Tentacles Into Healthcare with Google and Other Bets
- Apple Inc: Consumer Technology Meets Healthcare
- Amazon: Taking Logistics to the Next Level for Delivering Healthcare
- Echoes of the Final Frontier
- Notes
- Chapter 6 AI-Based Algorithms in Biology and Medicine