In Silico Dreams : How Artificial Intelligence and Biotechnology Will Create the Medicines of the Future.

Bibliographic Details
Main Author: Hilbush, Brian S.
Corporate Author: ProQuest (Firm)
Format: eBook
Language:English
Published: Newark : John Wiley & Sons, Incorporated, 2021.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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505 0 |a Cover -- Title Page -- Copyright Page -- About the Author -- About the Technical Editor -- Acknowledgments -- Contents at a Glance -- Contents -- Introduction -- What Does This Book Cover? -- Reader Support for This Book -- Chapter 1 The Information Revolution's Impact on Biology -- A Biological Data Avalanche at Warp Speed -- Tracking SARS-CoV-2 with Genomic Epidemiology -- Biology's Paradigm Shift Enables In Silico Biology -- Transitions and Computation in Cancer Research -- Structural Biology and Genomics -- Sequencing the Human Genome -- Computational Biology in the Twenty-First Century 
505 8 |a Applications of Human Genome Sequencing -- Analyzing Human Genome Sequence Information -- Omics Technologies and Systems Biology -- Notes -- Chapter 2 A New Era of Artificial Intelligence -- AI Steps Out of the Bronx -- From Neurons and Cats Brains to Neural Networks -- Machine Learning and the Deep Learning Breakthrough -- Deep Learning Arrives for AI -- Deep Neural Network Architectures -- Deep Learning's Beachhead on Medicine: Medical Imaging -- Limitations on Artificial Intelligence -- Notes -- Recommended Reading -- Chapter 3 The Long Road to New Medicines 
505 8 |a Medicine's Origins: The Role of Opium Since the Stone Age -- Industrial Manufacturing of Medicines -- Paul Ehrlich and the Birth of Chemotherapeutic Drug Discovery -- The Pharmaceutical Industry: Drugs and War-New Medicines in the Twentieth Century -- From Synthetic Antibiotics to the Search for New Drugs from the Microbial World -- Developing Therapeutics for Cancer -- Antifolates and the Emergence of DNA Synthesis Inhibitors -- Antibiotics as Cancer Chemotherapeutic Drugs -- Immunotherapy -- The Pharmaceutical Business Model in the Twenty-First Century 
505 8 |a R&D Productivity Challenges Within the Pharmaceutical Industry -- Sources of Pharmaceutical Innovation: Biotechnology and New Therapeutic Modalities -- Notes -- Recommended Reading -- Chapter 4 Gene Editing and the New Tools of Biotechnology -- Molecular Biology and Biological Information Flow -- Manipulating Gene Information with Recombinant DNA Technology -- Genetics, Gene Discovery, and Drugs for Rare Human Diseases -- Second-Generation Biotechnology Tools: CRISPR- Cas9 and Genome Editing Technologies -- Human Genome Editing and Clinical Trials 
505 8 |a Biotechnology to the Rescue: Vaccine Development Platforms Based on Messenger RNA -- Recommended Reading -- Notes -- Chapter 5 Healthcare and the Entrance of the Technology Titans -- Digital Health and the New Healthcare Investment Arena -- Assessing the Tech Titans as Disruptors in Healthcare -- Alphabet: Extending Its Tentacles Into Healthcare with Google and Other Bets -- Apple Inc: Consumer Technology Meets Healthcare -- Amazon: Taking Logistics to the Next Level for Delivering Healthcare -- Echoes of the Final Frontier -- Notes -- Chapter 6 AI-Based Algorithms in Biology and Medicine 
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