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|a Synthetic methods in drug discovery.
|n Volume 2 /
|c edited by David C. Blakemore, Paul M. Doyle, Yvette M. Fobian.
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| 264 |
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1 |
|a Cambridge :
|b Royal Society of Chemistry,
|c [2016]
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|c ©2016
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|a 1 online resource (xviii, 517 pages) :
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|v 53
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| 504 |
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|a Includes bibliographical references and index.
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| 505 |
0 |
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|a Lithium, magnesium, and copper: contemporary applications of organometallic chemistry in the pharmaceutical industry / Sajiv K. Nair, Benjamin N. Rocke and Scott Sutton -- C-N bond formation via hydrogen transfer / Daniel C. Schmitt and Anne-Marie D. Schmitt -- Synthesis of sulfonamides / Anne-Marie D. Schmitt and Daniel C. Schmitt -- Asymmetric methods and their use in the pharmaceutical industry / Peter D. Smith, Mark. A Graham, Rachel H. Munday, Craig S. Donald, Thomas M. McGuire and Robert E. Kyne Jr. -- Fluorination approaches / Duncan L. Browne and Paul Richardson -- The development of Csp3-Csp2 coupling methodology / Brian T. O'Neill -- Catalytic amide bond forming methods / Benjamin N. Atkinson, A. Rosie Chhatwal and Jonathan M.J. Williams -- Accessing novel molecular motifs and monomers / Subramanyam Chakrapani and Joseph S. Warmus.
|
| 520 |
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|a Building on key reactions presented in Volume 1, Synthetic Methods in Drug Discovery Volume 2 covers a range of important reaction types including organometallic chemistry, fluorination approaches and asymmetric methods as well as new and exciting areas such as Csp2-Csp3 couplings, catalytic amide bond forming reactions, hydrogen borrowing chemistry and methods to access novel motifs and monomers. This book provides both academic and industrial perspectives on key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Moreover, key opportunities in expanding chemical space are presented, including the increasingly important syntheses that introduce three-dimensional molecular shape. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.
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|a Drug development.
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|a Electronic books.
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|a Blakemore, David,
|e editor.
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| 700 |
1 |
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|a Doyle, Paul
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| 700 |
1 |
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|a Fobian, Yvette,
|e editor.
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|a Royal Society of Chemistry (Great Britain)
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|i Print version:
|t Synthetic methods in drug discovery.
|d Cambridge : Royal Society of Chemistry, [2016]
|z 9781782627876
|w (OCoLC)934606821
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0 |
|a RSC drug discovery series ;
|v 53.
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|u http://proxy.library.tamu.edu/login?url=https://dx.doi.org/10.1039/9781782627913
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|a Texas A&M University
|b College Station
|c Electronic Resources
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|e RM301.25 .S96 2016eb
|h Library of Congress classification
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| 998 |
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|a RM301.25 .S96 2016eb
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