Synthetic methods in drug discovery. Volume 1 /

Synthetic Methods in Drug Discovery Volume 1 focusses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging area...

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Bibliographic Details
Corporate Author: Royal Society of Chemistry (Great Britain)
Other Authors: Blakemore, David (Editor), Doyle, Paul (Chemist) (Editor), Fobian, Yvette (Editor)
Format: eBook
Language:English
Published: Cambridge : Royal Society of Chemistry, [2016]
Series:RSC drug discovery series ; 52.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Suzuki-Miyaura coupling / David Blakemore
  • Negishi coupling / Chris Limberakis
  • Hiyama coupling / Lee Boulton
  • Sonogashira coupling / Lee Boulton
  • Heck coupling / Alpay Dermenci and Jotham W. Coe
  • Palladium- and copper-catalysed C-N cross-coupling in drug discovery / Kevin D. Hesp and Julien Genovino
  • Chan-Lam coupling reaction: copper-promoted C-element bond oxidative coupling reaction with boronic acids / Patrick Y.S. Lam
  • C-H activation approaches to molecules / Elizabeth M. Beck, Antonia F. Stepan and Damien Webb
  • Palladium-catalyzed decarboxylative couplings / Christophe Linder and Nuria Rodríguez
  • New frontiers with transition metals / Brian S. Gerstenberger.