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0 |
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|a Synthetic methods in drug discovery.
|n Volume 1 /
|c edited by David C. Blakemore, Paul M. Doyle, Yvette M. Fobian.
|
| 264 |
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1 |
|a Cambridge :
|b Royal Society of Chemistry,
|c [2016]
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| 264 |
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4 |
|c ©2016
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|a 1 online resource (xviii, 455 pages)
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|a Drug discovery ;
|v 52
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| 504 |
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|a Includes bibliographical references and index.
|
| 505 |
0 |
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|a Suzuki-Miyaura coupling / David Blakemore -- Negishi coupling / Chris Limberakis -- Hiyama coupling / Lee Boulton -- Sonogashira coupling / Lee Boulton -- Heck coupling / Alpay Dermenci and Jotham W. Coe -- Palladium- and copper-catalysed C-N cross-coupling in drug discovery / Kevin D. Hesp and Julien Genovino -- Chan-Lam coupling reaction: copper-promoted C-element bond oxidative coupling reaction with boronic acids / Patrick Y.S. Lam -- C-H activation approaches to molecules / Elizabeth M. Beck, Antonia F. Stepan and Damien Webb -- Palladium-catalyzed decarboxylative couplings / Christophe Linder and Nuria Rodríguez -- New frontiers with transition metals / Brian S. Gerstenberger.
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| 520 |
|
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|a Synthetic Methods in Drug Discovery Volume 1 focusses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging areas such as decarboxylative coupling, and the uses of iron and nickel in coupling reactions are also covered. This book provides both academic and industrial perspectives on some key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.
|
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0 |
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|a Print version record.
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| 650 |
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0 |
|a Drug development.
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| 650 |
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2 |
|a Drug Discovery
|x methods.
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|a Drug development.
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|a Electronic books.
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1 |
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|a Blakemore, David,
|e editor.
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| 700 |
1 |
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|a Doyle, Paul
|c (Chemist),
|e editor.
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| 700 |
1 |
|
|a Fobian, Yvette,
|e editor.
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| 710 |
2 |
|
|a Royal Society of Chemistry (Great Britain)
|
| 776 |
0 |
8 |
|i Print version:
|t Synthetic methods in drug discovery.
|d Cambridge : Royal Society of Chemistry, [2016]
|z 9781782627876
|w (OCoLC)934606821
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| 830 |
|
0 |
|a RSC drug discovery series ;
|v 52.
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| 856 |
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|u http://proxy.library.tamu.edu/login?url=https://dx.doi.org/10.1039/9781782622086
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| 952 |
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|a Texas A&M University
|b College Station
|c Electronic Resources
|d Available Online
|t 0
|e RM301.25 .S96 2016eb
|h Library of Congress classification
|
| 998 |
f |
f |
|a RM301.25 .S96 2016eb
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|l Available Online
|