Toxicogenomics in predictive carcinogenicity /
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Cambridge, Englang :
Royal Society of Chemistry,
2016.
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| Series: | Issues in toxicology.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Introduction to Predictive Toxicogenomics for Carcinogenicity; Genomic Biomarkers in Cell-based Drug Screening; Toxicogenomics In Vitro: Gene Expression Signatures for Differentiating Genotoxic Mechanisms; In Vivo Signatures of Genotoxic and Non-Genotoxic Chemicals; Transcriptomic Dose-Response Analysis for Mode of Action and Risk Assessment; Using transcriptomics to evaluate thresholds in genotoxicity dose-response; Dissecting Modes of Action of Non-Genotoxic Carcinogens; Human Embryonic Stem Cells as Biological Models to Examine the Impact of Xenobiotics on the Genome and Epigenome; Novel Data Streams in the Assessment of Mutagenicity and Carcinogenicity: Implications for Cancer Hazard Assessment; Conazoles and Cancer, a Review; Application of Transcriptomics in Exposed Human Populations: Benzene as an Example; Toxicogenomics Case Study: Furan; The Parallelogram Approach to Assess Human Relevance of Toxicogenomics Derived Toxicity Pathways in Human Health Risk Assessment; Bioinformatics of Genomics in the Assessment of Cancer.