rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Modern NMR approaches to the structure elucidation of natural products
    part number: Volume 1
    part name: Instrumentation and software
  title info:
    title: Instrumentation and software
  name:
    name part: Martin, Gary
    role:
      role term: editor.
  name:
    name part: Rovnyak, David
    role:
      role term: editor.
  name:
    name part: Williams, Antony J.
    role:
      role term: editor.
  name:
    name part: Royal Society of Chemistry (Great Britain)
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2015
    copyright date: 2016
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: Strychnine's poisonous nature was known in 16th century Europe, and the alkaloid was isolated in pure form for the first time in 1818. Then began a more than century-long quest to unravel the structure of strychnine that led to two Nobel prizes, clearly without the assistance of the modern spectroscopic methods to which we now have access. In his 1963 report of the synthesis, Woodward said, "The tangled skein of atoms which constitutes its molecule provided a fascinating structural problem that was pursued intensively during the century just past, and was solved finally only within the last decade." The structure elucidation of complex natural products is facilitated today by access to modern instrumentation and experimental techniques. Using a modern 600 MHz NMR spectrometer equipped with a 1.7 mm cryogenic probe and a 1 mg sample, it is now possible to acquire a comprehensive suite of 2D NMR spectra that rigorously characterizes the complex structure of strychnine in a scant 24 hours. When the 2D NMR data are combined with Computer-Assisted Structure Elucidation methods, the structure can be solved in mere seconds. It is against this historical backdrop that these two volumes regarding the Structure Elucidation of Natural Products by NMR is set. Volume 1 discusses contemporary NMR approaches including optimized and future hardware and experimental approaches to obtain both the highest quality and most appropriate spectral data for analysis. Volume 2 considers data processing and algorithmic based analyses tailored to natural product structure elucidation and reviews the application of NMR to the analysis of a series of different natural product families including marine natural products, terpenes, steroids, and carbohydrates. These books, bringing together acknowledged experts, uniquely focus on the combination of experimental approaches and modern hardware and software applied to the structure elucidation of natural products. The volumes will be an essential reso…
  note: editors: Antony Williams, Gary Martin, David Rovnyak.
  note: Includes index.
  subject:
    topic: Natural products
    topic: Structure
  subject:
    topic: Nuclear magnetic resonance spectroscopy
  subject:
    topic: Nuclear magnetic resonance spectroscopy
  classification: QD415
  classification: 572/.33
  identifier: 1849735182
  identifier: 9781849735186
  identifier: 184973383X
  identifier: 9781849733830
  identifier: 1862:1688 Royal Society of Chemistry
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: UKRSC
    record creation date: 151119
    record change date: 20210308110838.0
    record identifier: in00004358274
    language of cataloging:
      language term: eng