Carbohydrates in drug design and discovery /
Focussing on drug discovery from key targets, this book comprehensively covers the new and recent discoveries in the area of carbohydrate drug discovery.
| Other Authors: | , , |
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| Format: | eBook |
| Language: | English |
| Published: |
Cambridge [UK] :
Royal Society of Chemistry,
[2015]
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| Series: | RSC drug discovery series ;
no. 43. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Tumor associated carbohydrate antigens; Lipopolysaccharides as microbe-associated molecular patterns; Carbohydrate protein interactions at the host-pathogen interface; Glyconanotechnology and disease; Glycodendrimers for drug discovery; Chemical glycobiology of infection; Glycosylated antitumor ether lipids; Synthesis of novel molecules for glycobiology and glycomedicine; The development of innovative strategies towards glycovaccines; Carbohydrates and glycomimetics in neurodiseases; Glycosyl-containing inhibitors of Matrix Metallo Proteinases; Design and synthesis of novel molecules as mechanistic probes for carbohydrate-mediated biological recognition; The development of the Haemophilus influenzae type b (Hib) vaccine using a synthetic antigen; Carbohydrate-Protein Interactios: A 3D view by NMR and modeling; Inhibition of enzyme activity (glycosides and gycosyl hydrolase enzymes) using multivalent analogs; Mycobacterium tuberculosis and C-type lectins; New tools for chemical medicine: From synthesis to applications