Venoms to drugs : venom as a source for the development of human therapeutics /

A comprehensive and up-to-date review on the potential of peptides and proteins from animal venoms as human therapeutics.

Bibliographic Details
Other Authors:	King, Glenn F. (Editor)
Format:	eBook
Language:	English
Published:	Cambridge, UK : Royal Society of Chemistry, [2015]
Series:	RSC drug discovery series ; 42.
Subjects:	Drug development. Peptide drugs. Pharmaceutical biotechnology. Venom > Therapeutic use. Venoms > therapeutic use. MEDICAL > Pharmacology. Therapy & therapeutics. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Venomous animals: evolution and ecology; Chemistry and structural biology of animal venoms; Venoms-based drug discovery: proteomic and transcriptomic approaches; Venoms-based drug discovery: bioassays, high-throughput screens, and target identification; Reptile venoms as a platform for drug development; Cone snail venoms as a platform for drug development; Scorpion venoms as a platform for drug development; Spider-venom peptides as a platform for drug development; Case study 1: development of the analgesic drugs Prialt® and Xen2174; Case study 2: development of exenatide for treatment of type 2 diabetes; Case study 3: development of ShK for the treatment of autoimmune diseases; Development of venom natriuretic peptides for treating congestive heart failure; Engineering venom peptides to improve their stability and bioavailability; Manufacturing of venom-derived therapeutic peptides; Venoms to drugs: prospects and pitfalls