New therapeutic strategies for type 2 diabetes : small molecule approaches /

Bibliographic Details
Other Authors: Jones, Robert M.
Format: eBook
Language:English
Published: Cambridge : Royal Society of Chemistry, [2012]
Series:RSC drug discovery series ; 27.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Type 2 diabetes: disease overview / Daniel M. Kemp
  • Marketed small molecule dipeptidyl peptidase IV (DPP4) inhibitors as a new class of oral anti-diabetics / Zhonghua Pei
  • SGLT2 inhibitors in development / William N. Washburn
  • Glucokinase activators in development / Kevin J. Filipski, Benjamin D. Stevens and Jeffrey A. Pfefferkorn
  • 11[beta]-hydroxysteroid dehydrogenase type 1 (11[beta]-HSD1) inhibitors in development / James S. Scott and Jasen Chooramun
  • Recent advances in PTP1B inhibitor development for the treatment of type 2 diabetes and obesity / Rongjun He, Li-Fan Zeng, Yantao He and Zhong-Yin Zhang
  • Recent advances in the discovery of GPR119 agonists / Unmesh Shah, Scott Edmondson and Jason W. Szewczyk
  • Acyl-CoA: diacylglycerol acyltransferase-1 inhibition as an approach to the treatment of type 2 diabetes / Robert L. Dow
  • Stearoyl-CoA desaturase 1 (SCD1) inhibitors: bench to bedside must only go through liver / Gang Liu
  • TGR5 agonists in development / Antonio Macchiarulo, Antimo Gioiello and Roberto Pellicciari
  • The discovery and development of MB07803, a second generation fructose-1,6-bisphosphatase inhibitor with improved pharmacokinetic properties, as a potential treatment of type 2 diabetes / Qun Dang, Paul D. van Poelje and Mark D. Erion
  • Inhibition of glycogen phosphorylase as a strategy for the treatment of type 2 diabetes / Brad R. Henke
  • SIRT1 activators in development / Robert B. Perni [and others]
  • Long-chain free fatty acid receptor agonists / Jonathan B. Houze
  • Glucagon receptor antagonists in development / Duane E. DeMong and M.W. Miller
  • ACC inhibitors in development / Matthew P. Bourbeau.