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|a Metabolism, pharmacokinetics and toxicity of functional groups :
|b impact of the building blocks of medicinal chemistry in ADMET /
|c edited by Dennis A. Smith.
|
| 264 |
|
1 |
|a Cambridge :
|b Royal Society of Chemistry,
|c 2010.
|
| 300 |
|
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|a 1 online resource
|
| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
|
| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a RSC drug discovery
|
| 500 |
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|a Electronic resource.
|
| 504 |
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|a Includes bibliographical references and index.
|
| 505 |
0 |
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|a Drug targets and their structural motifs -- ADMET for the medicinal chemist -- Carboxlic acids and their isosteres -- Primary, secondary and tertiary amines and isosteres -- Sulphonamide as an essential group -- 1, 2 and 3 ring phenyl and heterocyclic cores -- Heterocycles and phenyls as essential pharmacophore groups -- Peptides and peptidomimetic cores -- Peptides and peptidomimetics as functional groups -- Transition state functions -- Alcohols and carbonyls -- Future targets and chemistry needs.
|
| 520 |
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|a Until now, the area of drug metabolism and pharmacokinetics has been lacking in texts written for the Medicinal Chemist. This outstanding book, aimed at postgraduate medicinal chemists and those working in industry, fills this gap in the literature. Written by medicinal chemists and ADMET scientists with a combined experience of around 300 years, this aid to discovering drugs addresses the absorption, distribution, metabolism, excretion and toxicity (ADMET) issues associated with drugs. The book starts by describing drug targets and their structural motifs before moving on to explain ADMET for.
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| 588 |
0 |
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|a Online resource; title from title screen (viewed on June 15, 2010).
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1 |
2 |
|a Pharmacokinetics.
|0 https://id.nlm.nih.gov/mesh/D010599
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| 650 |
2 |
2 |
|a Chemistry, Pharmaceutical
|x methods.
|0 https://id.nlm.nih.gov/mesh/D002626Q000379
|
| 650 |
2 |
2 |
|a Pharmaceutical Preparations
|x metabolism.
|0 https://id.nlm.nih.gov/mesh/D004364Q000378
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| 650 |
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0 |
|a Drugs
|x Metabolism.
|0 http://id.loc.gov/authorities/subjects/sh85039737
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| 650 |
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0 |
|a Functional groups.
|0 http://id.loc.gov/authorities/subjects/sh91003889
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| 650 |
|
0 |
|a Pharmacokinetics.
|0 http://id.loc.gov/authorities/subjects/sh85100597
|
| 650 |
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0 |
|a Toxicity testing.
|0 http://id.loc.gov/authorities/subjects/sh85136327
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| 650 |
|
7 |
|a Drugs
|x Metabolism.
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|0 (OCoLC)fst00898845
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| 650 |
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7 |
|a Functional groups.
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| 650 |
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7 |
|a MEDICAL
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| 650 |
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|a Pharmacokinetics.
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|0 (OCoLC)fst01060250
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| 650 |
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7 |
|a Toxicity testing.
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|0 (OCoLC)fst01153336
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| 655 |
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|a Electronic books.
|2 local
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| 700 |
1 |
|
|a Smith, Dennis A.
|0 http://id.loc.gov/authorities/names/n85286334
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| 776 |
0 |
8 |
|i Print version:
|t Metabolism, pharmacokinetics, and toxicity of functional groups.
|d Cambridge, [England] : Royal Society of Chemistry, 2010
|z 9781849730167
|w (OCoLC)520767259
|
| 830 |
|
0 |
|a RSC drug discovery series.
|0 http://id.loc.gov/authorities/names/no2010092643
|
| 856 |
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|u http://proxy.library.tamu.edu/login?url=https://dx.doi.org/10.1039/9781849731102
|z Connect to the full text of this electronic book
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| 952 |
f |
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|a Texas A&M University
|b College Station
|c Electronic Resources
|d Available Online
|t 0
|e RM301.5 .M48 2010
|h Library of Congress classification
|
| 998 |
f |
f |
|a RM301.5 .M48 2010
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|l Available Online
|