Cover Image

RNA polymerases as molecular motors /

Show other versions (1)

The cell can be viewed as a 'collection of protein machines' and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists. To observe these machines in action, researchers have...

Full description

Bibliographic Details
Other Authors: Buc, Henri, Strick, Terence
Format: eBook
Language:English
Published: Cambridge, UK : RSC Pub., [2009]
Series:RSC biomolecular sciences.
Subjects:
Molecules.
RNA polymerases.
Acid Anhydride Hydrolases.
Adenosine Triphosphatases.
Biochemical Phenomena.
Chemical Phenomena.
DNA-Directed RNA Polymerases.
Enzymes and Coenzymes.
Enzymes.
Gene Expression.
Genetic Phenomena.
Hydrolases.
Investigative Techniques.
Macromolecular Substances.
Models, Molecular.
Models, Theoretical.
Molecular Motor Proteins.
Multiprotein Complexes.
Nucleotidyltransferases.
Phosphotransferases.
RNA Nucleotidyltransferases.
Transcription, Genetic.
Transferases.
SCIENCE > Life Sciences > Molecular Biology.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Where it begins : an overview of promoter recognition and open complex formation / Stephen Busby, Annie Kolb and Henri Buc
  • Opening the DNA at the promoter : the energetic challenge / Bianca Sclavi
  • Intrinsic in vivo modulators : negative supercoiling and the constituents of the bacterial nucleoid / Georgi Muskhelishvili and Andrew Travers
  • Transcription by RNA polymerases : from initiation to elongation, translocation and strand separation / Thomas A. Steitz
  • Single-molecule FRET analysis of the path from transcription initiation to elongation / Achillefs N. Kapanidis and Shimon Weiss
  • Real-time detection of DNA unwinding by Escherichia coli RNAP : from transcription initiation to termination / Terence R. Strick and Andrey Revyakin
  • The engine and the brake / Henri Buc and Terence Strick
  • Substrate loading, nucleotide addition, and translocation by RNA polymerase / Jinwei Zhang and Robert Landick
  • Regulation of RNA polymerase through its active center / Sergei Nechaev, Nikolay Zenkin and Konstantin Severinov
  • Kinetic modeling of transcription elongation / Lu Bai, Alla Shundrovsky and Michelle D. Wang
  • Mechanics of transcription termination / Evgeny Nudler
  • Past, present, and future of single-molecule studies of transcription / Carlos Bustamante and Jeffrey R. Moffitt.