Hormone-disruptive chemical contaminants in food /
Today, we are surrounded by a multitude of different chemicals that are essential components of our everyday life. As a consequence, there are various hazardous substances like dioxins, phthalates and flame-retardants circulating in the environment. These have an impact on ecosystems, wildlife and p...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Cambridge :
Royal Society of Chemistry,
[2012]
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| Series: | Issues in toxicology ;
11. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Introduction; Human exposure to food-borne chemicals; Persistent organic pollutants (POPs) in food; Chemicals targeting the reproductive axis; Hormone-disruptive chemicals: effects on coming generations through epigenetic mechanisms; Naturally occurring, hormonally active compounds in our diet; ER isoforms as targets for nutrients and xenoestrogens; From exposure to effects: Role of metabolism in the bioactivation/detoxication of food contaminants; Aryl hydrocarbon receptor (AhR) and bHLH-PAS transcription factors targeted by dietary and xenobiotic compounds; Small model organisms as tools in food safety research; Reporter animals as tools in food safety research; In silico screening approaches; Genomic approaches to toxicology and nutrition; Large-scale screening of chemicals; Summary and future perspectives.