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Animal models for neurodegenerative disease /

"In recent years, medical developments have resulted in an increase in human life expectancy. Some developed countries now have a larger population of individuals aged over 64 than those under 14. One consequence of the ageing population is a higher incidence of certain neurodegenerative disord...

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Bibliographic Details
Other Authors: Avila, Jesús, Hernández Perez, Félix, Lucas, José J.
Format: eBook
Language:English
Published: Cambridge, U.K. : Royal Society Chemistry, 2011.
Series:RSC drug discovery series ; 6.
Subjects:
Alzheimer's disease > Animal models.
Animal models in research.
Huntington's disease > Animal models.
Nervous system > Degeneration > Animal models.
Parkinson's disease > Animal models.
Disease Models, Animal.
Neurodegenerative Diseases > physiopathology.
Chemistry.
HEALTH & FITNESS > Diseases > Alzheimer's & Dementia.
MEDICAL > Neurology.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • 1. The Contribution of Transgenic Models to the Understanding of Alzheimer's Disease Progression and Therapeutic Development / Meredith A. Chabrier, Kara M. Neely, Nicholas A. Castello and Frank M. LaFerla
  • 2. Animal Models of Amyloid/PS-1 Pathology / Akihiko Takashima
  • 3. The Ying and Yang of the Reelin Signalling Pathway in Alzheimer's Disease Pathology / Eduardo Soriano, Daniela Rossi and Lluís Pujadas
  • 4. Transgenic Mice Overexpressing GSK-3[beta] as Animal Models for Alzheimer's Disease / Félix Hernández
  • t5. Invertebrate and Vertebrate Models of Tauopathies / Jügen Götz, Lars M. Ittner, Naeman N. Götz, Hong Lam and Hannah R. Nicholas
  • 6. Animal Models of Parkinson's Disease / Hardy J. Rideout and Leonidas Stefanis
  • 7. Animal Models and the Pathogenesis of Parkinson's Disease / José G. Castaño, Teresa Iglesias and Justo G. de Yébenes
  • 8. Neuroprotection in Parkinson's Disease / Alberto Pascual, Javier Villadiego, María Hidalgo-Figueroa, Simón Méndez-Ferrer, Raquel Gómez-Díaz, Juan José Toledo-Aral and José Lopez-Barneo
  • 9. Animal Models for ALS / Ritsuko Fujii and Toru Takumi
  • 10. Animal Models for Huntington's Disease / Zaira Ortega and José J. Lucas
  • 11. Mouse Models of Prion Protein Related Diseases / María Gasset and Adriano Aguzzi
  • 12. Mouse Models of Ischemia / David C. Henshall and Roger P. Simon
  • 13. A Non-transgenic Rat Model of Sporadic Alzheimer's Disease / Khalid Iqbal, Xiaochuan Wang, Julie Blanchard and Inge Grundke-Iqbal.