rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Biophysical approaches determining ligand binding to biomolecular targets
  name:
    name part: Dejaegere, Annick P.
  name:
    name part: Kieffer, Bruno.
  name:
    name part: Podjarny, A. D.
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2010
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational approaches to drug discovery and design. This book reviews the latest advances in the application of biophysics to the study of ligand binding. It provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand their binding mechanisms. Particular emphasis is given to the combined use of different techniques and their relative strengths and weaknesses. Consistency in the way each technique is described makes it easy for readers to select the most suitable protocol for their research. The introduction explains why some techniques are more suitable than others and emphasizes the possible synergies between them. The following chapters, all written by a specialist in the particular technique, focus on each method individually. The book finishes by describing how several complimentary techniques can be used together for maximum effectiveness. This book is suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available.
  note: editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer.
  note: Electronic resource.
  subject:
    topic: Ligand binding (Biochemistry)
  subject:
    topic: Ligand binding (Biochemistry)
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Biochemistry
  classification: QP517.L54 B56 2010
  classification: 572.33
  related item:
    title info:
      title: Biophysical approaches determining ligand binding to biomolecular targets
    origin info:
      publisher: Cambridge : Royal Society of Chemistry, 2010
    identifier: (OCoLC)495938622
  related item:
    title info:
      title: RSC biomolecular sciences
  identifier: 1849730091
  identifier: 1849732663
  identifier: 9781849730099
  identifier: 9781849732666
  identifier: T3394 Royal Society of Chemistry
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: UKRSC
    record creation date: 110519
    record change date: 20210728140512.0
    record identifier: in00004357812
    language of cataloging:
      language term: eng