Accounts in drug discovery : case studies in medicinal chemistry /

Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lea...

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Bibliographic Details
Other Authors: Barrish, Joel Charles, 1957-, Carter, Percy, Zahler, Robert
Format: eBook
Language:English
Published: Cambridge : Royal Society of Chemistry, [2010]
Series:RSC drug discovery series ; 4.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lead optimization starting from high throughput screening ""hits"" as well as rational, structure-based design. The chapters include ""follow-ons"" and ""next generation"" compounds that aim to improve upon first generation agents. This volume surveys the range of challenges commonly faced by medicinal.
Item Description:Electronic resource.
Physical Description:1 online resource
ISBN:1849731985
9781849731980
DOI:10.1039/9781849731980