rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Exploiting chemical diversity for drug discovery
  name:
    name part: Bartlett, Paul Allan
    name part: 1948-
  name:
    name part: Entzeroth, Michael.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2006
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xxiv, 420 pages) : illustrations (some color)
  abstract: Conceptual and technological advances in chemistry and biology have transformed the drug discovery process. Evolutionary pressure among the diverse scientific and engineering disciplines that contribute to the identification of biologically active compounds has resulted in synergistic improvements at every step in the process. Exploiting Chemical Diversity for Drug Discovery encompasses the many components of this transformation and presents the current state-of-the-art of this critical endeavour. From the theoretical and operational considerations in generating a collection of compounds to screen, to the design and implementation of high-capacity and high-quality assays that provide the most useful biological information, this book provides a comprehensive overview of modern approaches to lead identification. Beginning with an introductory overview, subsequent chapters address topics that include the design of chemical libraries and methods for optimizing their diversity; automated and accelerated chemistry; high throughput assay design and detection techniques; and strategies for data analysis and property optimization. Written by experts in the field, both academic and industrial, and illustrated in full colour, this book provides an excellent overview for current practitioners and will also serve as a stimulating resource for future generations. Researchers in organic and medicinal chemistry, the biological and pharmacological sciences, as well as those interested in allied computational and engineering disciplines will value the comprehensive and up-to-date coverage.
  table of contents: Exploiting Chemical Diversity for Drug Discovery_publicity; i_iv; v_viii; ix_x; xi_xxii; xxiii_xxiv; 001_032; 033_054; 055_090; 091_111; 112_136; 137_160; 161_183; 184_200; 201_232; 233_246; 247_262; 263_290; 291_312; 313_335; 336_363; 364_385; 386_404; 405_420.
  note: edited by Paul A. Bartlett, Michael Entzeroth.
  note: Electronic resource.
  note: Includes bibliographical references and index.
  subject:
    topic: Combinatorial Chemistry Techniques
  subject:
    topic: Drug Design
  subject:
    topic: Biological Science Disciplines
  subject:
    topic: Chemistry, Pharmaceutical
  subject:
    topic: Chemistry
  subject:
    topic: Drug Discovery
  subject:
    topic: Investigative Techniques
  subject:
    topic: Natural Science Disciplines
  subject:
    topic: Pharmacology
  subject:
    topic: Technology, Pharmaceutical
  subject:
    topic: Combinatorial chemistry
  subject:
    topic: Drugs
    topic: Design
  subject:
    topic: Biotechnology
  subject:
    topic: Chemistry
  subject:
    topic: Combinatorial chemistry
  subject:
    topic: Drugs
    topic: Design
  subject:
    topic: MEDICAL
    topic: Drug Guides
  subject:
    topic: MEDICAL
    topic: Nursing
    topic: Pharmacology
  subject:
    topic: MEDICAL
    topic: Pharmacology
  subject:
    topic: MEDICAL
    topic: Pharmacy
  subject:
    topic: Organic chemistry
  subject:
    topic: Science
  classification: RS419 .E87 2006eb
  classification: 615/.19
  related item:
    title info:
      title: Exploiting chemical diversity for drug discovery
    origin info:
      publisher: Cambridge, UK : Royal Society of Chemistry, ©2006
    identifier: (DLC) 2006445241
    identifier: (OCoLC)63703046
  related item:
    title info:
      title: RSC biomolecular sciences
  identifier: 1847552552
  identifier: 9781847552556
  identifier: 0854048421
  identifier: 9780854048427
  identifier: 10.1039/9781847552556 Royal Society of Chemistry
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: UKRSC
    record creation date: 080626
    record change date: 20210728140356.0
    record identifier: in00004357615
    language of cataloging:
      language term: eng