From DNA photolesions to mutations, skin cancer and cell death /

As modern day society takes an increasing interest in outdoor activities, its exposure to sunlight has never been greater. As a consequence, countries throughout the world are experiencing a dramatic increase in the incidences of skin carcinomas and melanomas. From DNA photolesions to mutations, ski...

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Bibliographic Details
Other Authors: Drouin, Régen, 1958-, Rouabhia, Mahmoud, 1957-, Sage, Evelyne
Format: eBook
Language:English
Published: Cambridge, UK : Royal Society of Chemistry, [2005]
Series:Comprehensive series in photochemistry & photobiology ; v. 5.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 0 0 |a From DNA photolesions to mutations, skin cancer and cell death /  |c editors, Évelyne Sage, Régen Drouin, Mahmoud Rouabhia. 
264 1 |a Cambridge, UK :  |b Royal Society of Chemistry,  |c [2005] 
264 4 |c ©2005 
300 |a 1 online resource (xxi, 311 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Comprehensive series in photochemistry and photobiology ;  |v v. 5 
500 |a Electronic resource. 
504 |a Includes bibliographical references and index. 
505 0 |a UVB and UVA induced formation of photoproducts within cellular DNA -- Chemical sequencing profiles of photosensitized DNA damage -- DNA damage induced by UVA radiation : role in solar mutagenesis -- Mutations induced by UV and sunlight -- Mechanisms and mutagenic consequences of photoproduct bypass by replicative and DNA damage bypass polymerases -- The Ogg1 protein of Saccharomyces cerevisiae: properties and biological functions -- The role of a yeast homologue of the human phosphatase activator hPTPA in the cellular response to oxidative DNA damage -- DNA repair in RNA polymerase I transcribed genes -- Global genome nucleotide excision repair: key players and their functions -- Efficient repair of UV-induced DNA damage in terminally differentiated human keratinocytes -- Reactivation of UV-damaged viruses and reporter genes in mammalian cells -- Transcription of p53-regulated genes under transcriptional stress : implications for nucleotide excision repair -- What a difference a wavelength makes : the role of p53 in nucleotide excision repair of UV-induced DNA damage -- p53 and p33ING1 : Role in nucleotide excision repair of UV-damaged DNA -- Nuclear and non-nuclear signals leading to UV-induced apoptosis -- Opposing roles of UV-induced apoptosis in early skin cancer -- Acquired activation of signalling pathways in skin tumours from DNA repair-deficient xeroderma pigmentosum patients -- Chaos theory and self-organized criticality describe the DNA damage signal transduction network. 
520 |a As modern day society takes an increasing interest in outdoor activities, its exposure to sunlight has never been greater. As a consequence, countries throughout the world are experiencing a dramatic increase in the incidences of skin carcinomas and melanomas. From DNA photolesions to mutations, skin cancer and cell death provides an authoritative source of information for photobiologists interested in the series of genetic events that occur in the skin, and eventually lead to cancer. With contributions from eminent scientists in the field, this book includes the latest information on DNA photolesions and repair, as well as the key mechanisms of solar UV in skin cancer initiation and development. Significant information relating to UV-induced photolesions and mechanisms of skin tumour occurrence is also included. By providing the basic phenomena underlying the science and an overview of the biological events that take place when cells are exposed to solar UV radiation, From DNA photolesions to mutations, skin cancer and cell death is suitable to all researchers interested in the process of photocarcinogenesis. 
588 0 |a Print version record. 
650 1 2 |a Skin Neoplasms  |x etiology.  |0 https://id.nlm.nih.gov/mesh/D012878Q000209 
650 2 2 |a Skin Physiological Phenomena  |x genetics.  |0 https://id.nlm.nih.gov/mesh/D012879Q000235 
650 2 2 |a Ultraviolet Rays  |x adverse effects.  |0 https://id.nlm.nih.gov/mesh/D014466Q000009 
650 2 |a Atmosphere.  |0 https://id.nlm.nih.gov/mesh/D001272 
650 2 |a Biochemical Phenomena.  |0 https://id.nlm.nih.gov/mesh/D001669 
650 2 |a Biological Phenomena.  |0 https://id.nlm.nih.gov/mesh/D001686 
650 2 |a Chemical Phenomena.  |0 https://id.nlm.nih.gov/mesh/D055598 
650 2 |a DNA Damage.  |0 https://id.nlm.nih.gov/mesh/D004249 
650 2 |a DNA Repair.  |0 https://id.nlm.nih.gov/mesh/D004260 
650 2 |a Delivery of Health Care.  |0 https://id.nlm.nih.gov/mesh/D003695 
650 2 |a Disease.  |0 https://id.nlm.nih.gov/mesh/D004194 
650 2 |a Ecological and Environmental Phenomena.  |0 https://id.nlm.nih.gov/mesh/D055669 
650 2 |a Electromagnetic Phenomena.  |0 https://id.nlm.nih.gov/mesh/D055590 
650 2 |a Environment and Public Health.  |0 https://id.nlm.nih.gov/mesh/D004778 
650 2 |a Environment.  |0 https://id.nlm.nih.gov/mesh/D004777 
650 2 |a Genetic Phenomena.  |0 https://id.nlm.nih.gov/mesh/D055614 
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650 2 |a Light.  |0 https://id.nlm.nih.gov/mesh/D008027 
650 2 |a Meteorological Concepts.  |0 https://id.nlm.nih.gov/mesh/D008685 
650 2 |a Neoplasms by Site.  |0 https://id.nlm.nih.gov/mesh/D009371 
650 2 |a Neoplasms.  |0 https://id.nlm.nih.gov/mesh/D009369 
650 2 |a Optical Phenomena.  |0 https://id.nlm.nih.gov/mesh/D055620 
650 2 |a Physical Phenomena.  |0 https://id.nlm.nih.gov/mesh/D055585 
650 2 |a Radiation, Nonionizing.  |0 https://id.nlm.nih.gov/mesh/D011840 
650 2 |a Radiation.  |0 https://id.nlm.nih.gov/mesh/D011827 
650 2 |a Skin Diseases.  |0 https://id.nlm.nih.gov/mesh/D012871 
650 2 |a Skin Neoplasms.  |0 https://id.nlm.nih.gov/mesh/D012878 
650 2 |a Skin Physiological Phenomena.  |0 https://id.nlm.nih.gov/mesh/D012879 
650 2 |a Skin and Connective Tissue Diseases.  |0 https://id.nlm.nih.gov/mesh/D017437 
650 2 |a Sunlight.  |0 https://id.nlm.nih.gov/mesh/D013472 
650 2 |a Ultraviolet Rays.  |0 https://id.nlm.nih.gov/mesh/D014466 
650 2 |a Weather.  |0 https://id.nlm.nih.gov/mesh/D014887 
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700 1 |a Rouabhia, Mahmoud,  |d 1957-  |0 http://id.loc.gov/authorities/names/n97800962 
700 1 |a Sage, Evelyne.  |0 http://id.loc.gov/authorities/names/nb2005019240 
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