DNA-targeting molecules as therapeutic agents /
This book explains key aspects of the progress that has been made towards understanding how drugs can bind specifically to nucleic acids, and thus underpin the endeavour to make gene targeting a reality. The binding of drugs to DNA is a fast developing area of research with important applications in...
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| Format: | eBook |
| Language: | English |
| Published: |
Cambridge :
Royal Society of Chemistry,
2018.
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| Series: | Chemical biology series ;
no. 7. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | This book explains key aspects of the progress that has been made towards understanding how drugs can bind specifically to nucleic acids, and thus underpin the endeavour to make gene targeting a reality. The binding of drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Early chapters cover methodologies to evaluate DNA-interactive agents and then the book provides examples of DNA-interactive molecules and technologies in development as therapeutic agents and treats in depth topics such as DNA-binding metal complexes, peptide and polyamide-DNA interactions. |
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| Item Description: | Includes index. |
| Physical Description: | 1 online resource (414 pages) |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1788012925 1788014286 9781788012928 9781788014281 |
| DOI: | 10.1039/9781788012928 |