Cyclic peptides : from bioorganic synthesis to applications /

This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.

Bibliographic Details
Other Authors: Donk, Wilfred A. van der (Editor), Koehnke, Jesko (Editor), Naismith, James (Editor)
Format: eBook
Language:English
Published: Cambridge : Royal Society of Chemistry, [2017]
Series:Chemical biology series ; no. 6.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • An Introduction to Cyclic Peptides; The Biosynthesis of Cyclic Peptides
  • RiPPs
  • an Overview; Thioesterase Domain-mediated Macrocyclization of Non-ribosomal Peptides; The Biosynthetic Machinery and its Potential to Deliver Unnatural Cyclic Peptides; Modulation of Protein-Protein Interactions Using Cyclic Peptides; Biology and Synthesis of the Argyrins; Peptide Cross-links Catalyzed by Metalloenzymes in Natural Product Biosynthesis; Double-click Stapled Peptides for Inhibiting Protein-Protein Interactions; Libraries of Head-to-Tail Peptides; An Introduction to Bacterial Lasso Peptides; Biological Synthesis and Affinity-Based Selection of Small Macrocyclic Peptide Ligands; Mass Spectrometric Analysis of Cyclic Peptides; Experimental and Computational Approaches to the Study of Macrocycle Conformations in Solution; Trends in Cyclotide Research; Cyclic Peptides
  • A Look to the Future.