rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Introduction to Synthetic Biology
    sub title: About Modeling, Computation, and Circuit Design
  name:
    name part: Marchisio, Mario Andrea
    role:
      role term: creator
    role:
      role term: author.
    role:
      role term: http://id.loc.gov/vocabulary/relators/aut
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: si
    date issued: 2018
    issuance: monographic
  language:
    language term: eng
  physical description:
    reformatting quality: access
    form: remote
    extent: 1 online resource (XII, 187 pages 91 illustrations, 74 illustrations in color) : online resource.
  abstract: The textbook is based on the lectures of the course "Synthetic Biology" for Master's students in biology and biotechnology at the Harbin Institute of Technology. The goal of the textbook is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab. Concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis and optimization are presented. At the end of the textbook, a chapter contains a description of structural motifs (e.g. positive and negative feedback loops, Boolean gates) that carry out specific functions and can be combined into larger networks. Moreover, several chapters show how to build up (an analyse, where possible) models for synthetic gene circuits with four different open-source software id est COPASI, XPPAUT, BioNetGeN, and Parts and Pools-ProMoT.
  table of contents: Chapter 1: Introduction -- Chapter 2: Modeling: choosing a kinetics -- Chapter 3: Modeling at computer: getting started -- Chapter 4: Stochastic modeling -- Chapter 5: Steady states -- Chapter 6: Stability analysis: hysteresis and oscillations -- Chapter7: Toggle switch: dynamics and steady states -- Chapter 8: Rule-based modeling -- Chapter 9: Gene circuit modular computational design -- Chapter 10: Parameter analysis -- Chapter 11: Circuit analysis with COPASI -- Chapter 12: Circuit motifs.
  note: by Mario Andrea Marchisio.
  note: Electronic resource.
  subject:
    topic: Biomedical engineering
  subject:
    topic: Biological models
  subject:
    topic: Biotechnology
  subject:
    topic: Biomedical Engineering/Biotechnology
  subject:
    topic: Systems Biology
  subject:
    topic: Biotechnology
  classification: R856-R857
  classification: 610.28
  related item:
    title info:
      title: Springer eBooks
  related item:
    title info:
      title: Learning materials in biosciences
  identifier: 9789811087523
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record creation date: 180514
    record change date: 20240730210432.4
    record identifier: in00004008137