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Photomedicine and stem cells : the Janus face of photodynamic therapy (PDT) to kill cancer stem cells, and photobiomodulation (PBM) to stimulate normal stem cells /

Bibliographic Details
Main Authors: Abrahamse, Heidi (Author), Hamblin, Michael R. (Author)
Format: eBook
Language:English
Published: San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) : Morgan and Claypool Publishers, [2017]
Series:IOP (Series). Release 4.
IOP concise physics.
Subjects:
Phototherapy.
Stem cells.
Phototherapy > methods.
Stem Cells.
Medical physics.
SCIENCE / Life Sciences / Biophysics.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • 1. Introduction
  • 1.1. The Janus face of photomedicine
  • 1.2. Photodynamic therapy--the killer
  • 1.3. Cellular effects of PDT
  • 1.4. Photobiomodulation--the healer
  • 2. Cancer stem cells
  • 2.1. Evidence for the existence of CSCs and their characteristic markers
  • 2.2. Role in tumor recurrence
  • 2.3. Anti-CSC approaches
  • 3. PDT and cancer stem cells
  • 3.1. PDT and cancer treatment
  • 3.2. PDT and CSCs
  • 3.3. ABC transporters and ABCG2
  • 3.4. ABCG2 in cancer stem cells
  • 3.5. ABCG2 and PS efflux
  • 3.6. Efflux pump inhibition and PDT
  • 3.7. Evidence of effect of PBM on CSCs
  • 4. Normal stem cells
  • 4.1. Developmental biology
  • 4.2. Markers and phenotypes
  • 4.3. Stem cell niches
  • 4.4. Asymmetric and symmetric stem cell division
  • 4.5. Differentiation programs
  • 4.6. Stem cell therapies
  • 5. PBM and stem cells
  • 5.1. Introduction
  • 5.2. Mechanisms of PBM/LLLT
  • 5.3. Why should PBM particularly affect stem cells?
  • 5.4. Role of stem/progenitor cells in PBM/LLLT
  • 5.5. PBM to the bone marrow
  • 6. PBM and adipose-derived mesenchymal stem cells
  • 6.1. Adipose-derived stem cells
  • 6.2. PBM and ADSCs
  • 6.3. Studies from the Abrahamse laboratory
  • 6.4. Work from the Hamblin laboratory
  • 7. PBM and dental stem cells
  • 7.1. Introduction
  • 7.2. PBM and dental stem cells
  • 7.3. PBM and tooth regeneration
  • 7.4. TGF-β mediates PBM induction of dentin repair in vivo
  • 7.5. Conclusion
  • 8. The role of stem cells and progenitor cells in PBM for brain disorders
  • 8.1. Introduction
  • 8.2. PBM and the brain
  • 8.3. PBM for stroke
  • 8.4. PBM for traumatic brain injury
  • 8.5. PBM/LLLT for other brain disorders
  • 8.6. Conclusion
  • 9. PBM and stem cells in hair regrowth
  • 9.1. Introduction to hair growth
  • 9.2. Skin, hair follicles, and stem cells
  • 9.3. Alopecia
  • 9.4. PBM for alopecia
  • 10. Conclusion.