NMR data interpretation explained : understanding 1D and 2D NMR spectra of organic compounds and natural products /
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| Format: | eBook |
| Language: | English |
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Hoboken, New Jersey :
Wiley,
2016.
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| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Title Page; Copyright; Examples; Preface; Acknowledgments; About the Companion Website; Chapter 1: Spectroscopy and the Proton NMR Experiment; 1.1 What is the Structure of a Molecule?; 1.2 Mass Spectrometry; 1.3 Infrared (IR) Spectroscopy; 1.4 Ultraviolet (UV) and Visible Spectroscopy; 1.5 A Highly Simplified View of the NMR Experiment; Chapter 2: Chemical Shifts and Splitting Patterns; 1 Chemical Shifts in the Proton Spectrum; 2 Splitting: The Effect of One Neighbor: A Doublet; 3 Splitting: The Effect of two Neighbors: A Triplet; 4 Splitting: The Effect of Three Neighbors: A Quartet.
- 5 Splitting: The Effect of "n" Neighbors: A Multiplet6 Using Splitting Patterns to Choose from a Group of Isomers; 7 Peak Intensities (Peak Areas) and the Number of Protons in A Peak; 8 Publication Format for Proton NMR Data; 9 Recognizing Common Structure Fragments; 10 Overlap in Proton NMR Spectra. Example: 1-Methoxyhexane; 11 Protons Bound to Oxygen: OH Groups. Example: 2-Ethyl-1-Butanol; 12 Summary of Chemical Shifts and Splitting Patterns; Chapter 3: Proton (1H) NMR of Aromatic Compounds; 1 Benzene: The Aromatic Ring Current and The Shielding Cone; 2 Monsubstituted Benzene: X-C6H5.
- 3 Disubstituted Benzene: X C6H4 Y4 Coupling Between Aromatic Ring Protons and Substitutent Protons; Homonuclear Decoupling; 5 Trisubstituted Aromatic Rings: The Ab2 System; 6 Other Aromatic Ring Systems: Heteroaromatics, Five-Membered Rings and Fused Rings; 7 Summary of New Concepts: Proton NMR of Aromatic Compounds; Chapter 4: Carbon-13 (13C) NMR; 1 Natural Abundance and Sensitivity of 13C; 2 Proton Decoupling-Removing the Splitting Effect of Nearby Protons; 3 Intensity of 13C Peaks-Symmetry and Relaxation; 4 Chemical Shifts of Carbon-13 (13C) Nuclei.
- 5 Quaternary Carbons: the Carbonyl Group6 Simple Aromatic Compounds: Substituent Effects on 13C Chemical Shifts; 7 Highly Oxygenated Benzene Rings and Coumarin; 8 Fused Rings and Heteroaromatic Compounds; 9 Edited 13C Spectra: DEPT; 10 The Effect of Other Magnetic Nuclei on the 13C Spectrum: 31P, 19F, 2H and 14N; 11 Direct Observation of Nuclei Other Than Proton (1H) and Carbon (13C); Chapter 5: Alkenes (Olefins); 1 Proton Chemical Shifts of Simple Olefins; 2 Short-Range (Two and Three Bond) Coupling Constants (J Values) in Olefins; 3 The Allylic Coupling: A Long-Range (Four-Bond) J Coupling.
- 4 Long-Range Olefin Couplings in Cholesterol: The bis-Allylic Coupling (5J)5 Carbon-13 Chemical Shifts of Hydrocarbon Olefins (Alkenes); 6 Resonance Effects on Olefinic 13C Chemical Shifts; 7 Alkynes; Chapter 6: Chirality and Stereochemistry: Natural Products; 1 The Molecules of Nature; 2 Chirality, Chiral Centers, Chiral Molecules, and the Chiral Environment; 3 The AB System; 4 Detailed Analysis of the AB Spectrum: Calculating the Chemical Shifts; 5 The ABX System; 6 Variations on the ABX Theme: ABX3, ABX2 and ABXY; 7 The Effect of Chirality on 13C Spectra. Diastereotopic Carbons.