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Drug design : cutting edge approaches /

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Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead...

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Bibliographic Details
Corporate Author: Knovel (Firm)
Other Authors: Flower, Darren R.
Format: eBook
Language:English
Published: Cambridge, UK : Royal Society of Chemistry, [2002]
Series:Special publication (Royal Society of Chemistry (Great Britain)) ; no. 279.
Subjects:
Drugs > Design > Congresses.
Drugs > Design > Mathematical models > Congresses.
Artificial intelligence > Medical applications > Congresses.
Drugs > Research > Methodology > Congresses.
Médicaments > Conception.
Pharmacologie moléculaire > Simulation par ordinateur.
Pharmacologie expérimentale > Simulation par ordinateur.
Chemistry.
MEDICAL > Drug Guides.
MEDICAL > Nursing > Pharmacology.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
Science.
Drug Design.
Combinatorial Chemistry Techniques.
Computer Simulation.
Models, Chemical.
Congresses.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Molecular informatics : sharpening drug design's cutting edge
  • High-throughput X-ray crystallography for drug discovery
  • Trawling the genome for G protein-coupled receptors : the importance of integrating bioinformatic approaches
  • Virtual screening of virtual libraries : an efficient startegy for lead generation
  • Virtual techniques for lead optimisation
  • The impact of physical organic chemistry on the control of drug-like properties
  • Mutagenesis and modelling highlight the critical nature of the TM2-loop-TM3 region of biogenic amine GPCRs
  • Computational vaccine design.