Microbial glycobiology : structures, relevance and applications /
This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of bas...
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| Other Authors: | , , , |
| Format: | eBook |
| Language: | English |
| Published: |
Amsterdam ; Boston :
Academic Press/Elsevier,
[2009]
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| Edition: | 1st ed. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Part I. Microbial glycolipids, glyoproteins and glycopolymersß 1. Overview of the glycosylated components of the bacterial cell wallßß 2. Bacterial cell wall envelope peptidoglycanßß 3. Core oligosaccharide and lipid A components of lipopolysaccharidesßß 4. O-Specific polysaccharides of Gram-negative bacteriaßß 5. Teichoic acids, lipoteichoic acids, and related cell wall glycopolymers of Gram-positive bacteriaßß 6. Bacterial capsular polysaccharides and exopolysaccharidesßß 7. Bacterial surface layer glycoproteins and "non-classical" secondary cell wall polymersßß 8. Glycosylation of bacterial and archaeal flagellinsßß 9. Glycosylated components of the mycobacterial cell wall: structure and functionßß 10. Glycoconjugate structure and function in fungal cell wallsßß 11. Cytoplasmic carbohydrate molecules: trehalose and glycogenßß 12. Glycosylated compounds of parasitic protozoaßß 13. Analytical approaches towards the structural characterization of microbial wall glycopolymersßß 14. Single-molecule characterization of microbial polysaccharidesßß 15. Viral surface glycoproteins in carbohydrate recognition: structure and modelingßPart II. Synthesis of microbial glycosylated components; A. Biosynthesis and biosynthetic processesß 16. Biosynthesis of bacterial peptidoglycanßß 17. Biosynthesis and membrane assembly of lipid Aßß 18. Biosynthesis of O-antigen chains and assemblyßß 19. Biosynthesis of cell wall teichoic acid polymersßß 20. Biosynthesis and assembly of capsular polysaccharidesßß 21. Biosynthesis of the mycobacterial cell envelope componentsßß 22. Biosynthesis of fungal and yeast glycansßB. Chemical synthesisßß 23. Chemical synthesis of bacterial lipid Aßß 24. Chemical synthesis of the core oligosaccharide of bacterial lipopolysaccharideßß 25. Chemical synthesis of lipoichoic acid and derivativesßß 26. Chemical synthesis of parasitic glycoconjugates and phosphoglycansß Part III. Microbe-host glycosylated interactionsßß 27. Bacterial lectin-like interactions in cell recognition and adhesionßß 28. Lectin-like interactions in virus-cell recognition: human immunodeficiency virus and C-type lectin interactionsßß 29. Sialic acid-specific microbial lectinsßßß 30. Bacterial toxins and their carbohydrate receptors at the host-pathogen interfaceßß 31. Toll-like receptor recognition of lipoglycans, glycolipids and lipopeptidesßß 32. NOD receptor recognition of peptidoglycanßß 33. Microbial interaction with mucus and mucinsßß 34. Mannose-fucose recognition by DC-SIGNßß 35. Host surfactant proteins in microbial recognitionßß 36. T-cell recognition of microbial lipoglycans and glycolipidsß Part IV. Biological relevance of microbial glycosylated components; A. Environmental relevanceßß 37. Extracellular polymeric substances in microbial biofilmsßß 38. Physico-chemical properties of microbial glycopolymersßß 39. Microbial biofilm-related polysaccharides in biofouling and corrosionßß 40. Microbial glycosylated components in plant diseaseßßB. Medical relevanceßß 41. Antigenic variation of microbial surface glycosylated moleculesßß 42. Phase variation of bacterial surface glycosylated molecules in immune evasionßß 43. Molecular mimicry of host glycosylated structures by bacteriaßß 44. Role of microbial glycosylation in host cell invasionß Part V. Biotechnological and medical applicationsßß 45. Exopolysaccharides produced by lactic acid bacteria in food and probiotic applicationsßß 46. Industrial exploitation by genetic engineering of bacterial glycosylation systemsßß 47. Glycomimetics as inhibitors in anti-infection therapyßß 48. Bacterial polysaccharide vaccines: glycogonjugates and peptide-mimeticsßß 49. Immunomodulation by zwitterionic polysaccharidesßß 50. Future potential of glycomics in microbiology and infectious diseasesß