rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Emerging roles for hippocampal adult neural stem cells in memory
  name:
    name part: Friedman, Aaron R.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Kaufer, Daniela
    role:
      role term: author.
  type of resource: text
  genre: abstract or summary
  genre: Electronic books.
  origin info:
    place:
      place term: cau
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    reformatting quality: access
    form: remote
    extent: 1 online resource (ix, 29 pages) : illustrations.
  abstract: Approximately 50 years ago, newly generated neurons were discovered in the adult hippocampus of the rat brain. This discovery contradicted a key principle in mammalian developmental neurobiology--that all the neurons of the brain are made during early development--and led to intensive study to find out how new neurons are generated and how the process of neurogenesis is regulated. Since then, a unique population of adult neural stem cells has been identified, and many of the molecular pathways that control their self-renewal, proliferation, and cell fate have been elucidated. However, the presence of new neurons in the adult brain also poses intriguing functional questions that have, as yet, gone largely unanswered. Why is adult neurogenesis restricted to select brain regions? What functional benefit do these new cells confer? Indeed, the field of adult neurogenesis offers a unique opportunity to study naïve neurons as they mature, form connections with existing neural networks, and begin to participate in information processing. We review the basics of adult NSC biology and the maturation of newborn neurons. In particular, we focus on new neurons in the hippocampus, and how they contribute to function in this key memory-forming structure of the brain.
  table of contents: Acknowledgments -- Introduction -- A day in the life of a hippocampal neural stem cell -- Dynamic regulation of neurogenesis and maturation -- The function of new neurons -- Neurogenesis as a regulator of affective state -- Conclusions -- References -- Author biographies.
  target audience: specialized
  note: Aaron R. Friedman, Daniela Kaufer.
  note: Part of: Colloquium digital library of life sciences.
  note: Series from website.
  note: Abstract freely available; full-text restricted to subscribers or individual document purchasers.
  note: Google book search
  note: Google scholar
  note: Also available in printing.
  note: Mode of access: World Wide Web.
  note: System requirements: Adobe Acrobat reader.
  note: Includes bibliographical references (pages 21-27).
  subject:
    topic: Developmental neurobiology
  subject:
    topic: Hippocampus (Brain)
  subject:
    topic: Neural stem cells
  subject:
    topic: Developmental Biology
  subject:
    topic: Hippocampus
  subject:
    topic: Neural Stem Cells
  subject:
    topic: Neurobiology
  subject:
    topic: adult hippocampal neural stem cells
  subject:
    topic: dentate gyrus
  subject:
    topic: emotional memory
  subject:
    topic: gliogenesis
  subject:
    topic: hippocampus
  subject:
    topic: learning and memory
  subject:
    topic: neurogenesis
  subject:
    topic: pattern separation
  classification: QP363.5 .F754 2014
  classification: 612.8
  classification: WL 102.5 F754e 2014
  related item:
    note: Google book search
  related item:
    note: Google scholar
  related item:
    title info:
      title: Colloquium digital library of life sciences
  related item:
    title info:
      title: Colloquium series on stem cell biology ; # 5
  identifier: 9781615044771
  identifier: 9781615044764
  identifier: http://proxy.library.tamu.edu/login
  access condition: Abstract freely available; full-text restricted to subscribers or individual document purchasers.
  record info:
    record content source: CaBNVSL
    record creation date: 140115
    record change date: 20210728125133.0
    record identifier: in00003638907
    language of cataloging:
      language term: eng