Peripheral arterial disease : pathophysiology and therapeutics /
| Main Authors: | , , , |
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| Format: | eBook |
| Language: | English |
| Published: |
San Rafael, California (1537 Fourth Street, San Rafael, CA 94901 USA) :
Morgan & Claypool,
2013.
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| Series: | Colloquium digital library of life sciences.
Colloquium series on integrated systems physiology ; # 40. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Abstract: | Peripheral arterial disease (PAD) is a cardiovascular disorder of the peripheral vasculature due to progressive atherosclerotic stenosis of conduit arteries restricting blood flow to tissues. PAD is typically a disease of older individuals, and the incidence of PAD continues to rise due to an increase in cardiometabolic disease and an aging population. Importantly, "all cause" and cardiovascular morbidity and mortality are significantly increased in PAD patients. PAD diagnosis remains a significant challenge, as a large number of patients are asymptomatic. Moreover, PAD results in a significant financial and societal burden with underutilized diagnostics and limited effective therapies. Here we discuss PAD signs and symptoms, pathophysiological mechanisms, current management, and future disease targets and possible therapeutic treatments for PAD. |
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| Item Description: | Part of: Colloquium digital library of life sciences. Series from website. |
| Physical Description: | 1 online resource (viii, 74 pages) : illustrations. Also available in printing. |
| Format: | Mode of access: World Wide Web. System requirements: Adobe Acrobat reader. |
| Bibliography: | Includes bibliographical references (pages 55-71). |
| ISBN: | 9781615045990 (electronic bk.) |
| ISSN: | 2154-5626 ; |
| DOI: | 10.4199/C00086ED1V01Y201307ISP040 |
| Access: | Abstract freely available; full-text restricted to subscribers or individual document purchasers. |