The actin cytoskeleton and the regulation of cell migration /
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :
Morgan and Claypool,
[2013]
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| Series: | Colloquium digital library of life sciences.
Colloquium series on building blocks of the cell ; # 5. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- 1. Introduction
- 2. The fundamentals of actin polymerization
- 2.1 Actin structure
- 2.2 Polymerization and nucleation
- 2.3 Directionality and treadmilling
- 2.4 Actin and ATP
- 3. Accessory proteins regulate actin polymerization and assembly
- 3.1 Nucleation proteins
- 3.2 Bundling proteins
- 3.3 Capping proteins
- 3.4 Severing proteins
- 3.5 Contraction
- 4. Cellular actin structure
- 4.1 Visualizing the actin cytoskeleton
- 4.2 The cell cortex
- 4.3 The lamellipodium and lamella
- 4.4 Ruffles
- 4.5 Filopodia
- 4.6 Focal adhesions
- 4.7 Stress fibers
- 4.8 Podosomes
- 4.9 Pseudopodia
- 5. Cell migration
- 5.1 Randomness and directionality
- 5.2 Polarization
- 5.2.1 Rho family GTPases
- 5.2.2 Par polarity complexes
- 5.2.3 The phospholipids PI(3,4,5)P3 and PI(4,5)P2
- 5.3 Protrusion
- 5.3.1 Lamellipodial protrusion
- 5.4 Filopodial protrusion
- 5.5 Adhesion
- 5.6 De-adhesion and retraction
- 6. Summary of cell migration
- References
- Author biography.