Membrane nanodomains /

Bibliographic Details
Main Author:	Silvius, John Robert, 1954-
Format:	eBook
Language:	English
Published:	San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan and Claypool, [2013]
Series:	Colloquium digital library of life sciences. Colloquium series on building blocks of the cell ; # 1.
Subjects:	Cell membranes. Cell Membrane. biological membrane membrane lipids membrane proteins membrane curvature lipid phases lipid rafts cholesterol protein-protein interactions protein-lipid interactions fluorescence microscopy electron microscopy single-particle fluorescence super-resolution microscopy mass spectrometry epithelial cells lymphocytes mast cells cell signaling membrane traffic Electronic books.
Online Access:	Connect to the full text of this electronic book

Description
Abstract:	Many membranes in eukaryotic cells are inhomogeneous structures in which various membrane components are nonrandomly distributed, forming diverse types of 'domains.' Some membrane domains have long been well known, because they are sufficiently large, long-lived, and morpho - logically well defined to be characterized using classical microscopic and biochemical approaches. However, new technologies have revealed the presence in membranes of smaller, often highly dynamic 'nanodomains' that also play key roles in membrane function. Our current understanding of the diversity, the properties, and the functions of nanodomains is still very limited and, in some cases, controversial. Nonetheless, it is clear that many important aspects of membrane biology arise from features of membrane organization that 'play out' on spatial and temporal scales that are only now becoming experimentally accessible in living systems. In this book, we will discuss properties and interactions of membrane molecules that lead to nanodomain formation, new and emerging technologies by which nanodomains can be studied, and experimental examples that illustrate both highlights and current limitations of our present knowledge of the properties of membrane nanodomains in various cell types.
Item Description:	Part of: Colloquium digital library of life sciences. Series from website. Electronic resource.
Physical Description:	1 online resource (viii, 103 pages) : illustrations Also available in printing.
Format:	Mode of access: World Wide Web. System requirements: Adobe Acrobat reader.
Bibliography:	Includes bibliographical references (pages 87-103).
ISBN:	9781615046218 (electronic bk.)
Access:	Abstract freely available; full-text restricted to subscribers or individual document purchasers.