Table of Contents:
  • 1. The stress response system
  • 1.1 Introduction
  • 1.2 Overview of stress responding
  • 1.2.1 Sympathoadrenal system (SAS)
  • 1.2.2 Hypothalamic-pituitary-adrenal (HPA) axis
  • 1.2.3 Stress-related behaviours
  • 1.2.4 Pathophysiological consequences of stress responding
  • 1.2.5 Sex differences
  • 2. The human brain
  • 2.1 Basic principles of neural communication
  • 2.1.1 The action potential and release of neurotransmitters
  • 2.1.2 Regional specialization
  • 3. Developmental programming of the stress response
  • 3.1 Introduction
  • 3.2 Vulnerability versus resilience
  • 3.3 Animal models
  • 3.4 Potential role of maternal care
  • 3.5 Importance of prefrontal cortical areas
  • 3.6 Epigenetics
  • 3.6.1 Overview of epigenetic mechanisms
  • 3.6.2 Epigenetic programming of brain regions involved in stress responding
  • 4. The importance of adolescence
  • 4.1 Introduction
  • 4.2 Overview of pubertal /adolescent physical development
  • 4.3 The adolescent transition
  • 4.4 Adolescent stress responding and ongoing brain development
  • 4.4.1 Structural changes
  • 4.4.2 Functional changes
  • 4.4.3 Neurotransmitter systems
  • 5. Understanding adult stress responding using a developmental framework
  • 5.1 Discussion
  • 5.2 Conclusion
  • Bibliography
  • Author biographies.