Local control of microvascular perfusion /

Bibliographic Details
Main Author:	Hill, Michael A.
Other Authors:	Davis, Michael J.
Format:	eBook
Language:	English
Published:	San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan and Claypool, [2013]
Series:	Colloquium digital library of life sciences. Colloquium series on integrated systems physiology ; # 35.
Subjects:	Blood > Circulation > Regulation. Microcirculation. Perfusion (Physiology) Blood Circulation. Perfusion. arterioles autoregulation blood flow control conducted vasomotor responses flow-mediated responses metabolic myogenic Electronic books.
Online Access:	Connect to the full text of this electronic book

Description
Abstract:	Local control of microvascular perfusion refers to the ability of individual tissues to maintain a relative constancy of hemodynamics in the face of changing perfusion pressure while meeting metabolic demands appropriately. The regulation of local blood flow, or autoregulation, and its underlying mechanisms have been a subject of considerable interest for over 100 years. Particular focus has been placed on the acute interaction of myogenic (pressure-induced) and metabolic (local production of vasodilator metabolites) parameters and how they interact with flow (shear stress)-dependent and conduction-based mechanisms to produce integrated local vascular network responses (for example, as seen during reactive and functional hyperemia). This monograph discusses each of these vasoregulatory phenomena while also considering evidence for their underlying cellular mechanisms. Further, an attempt is made to integrate the information into complex in vivo situations and consider their relevance to pathophysiological situations.
Item Description:	Electronic resource. Part of: Colloquium digital library of life sciences. Series from website.
Physical Description:	1 online resource (xiii, 133 pages) : illustrations Also available in printing.
Format:	Mode of access: World Wide Web. System requirements: Adobe Acrobat reader.
Bibliography:	Includes bibliographical references (pages 99-133).
ISBN:	9781615044375 (electronic bk.)
ISSN:	2154-5626 ;
DOI:	10.4199/C00061ED1V01Y201206ISP035
Access:	Abstract freely available; full-text restricted to subscribers or individual document purchasers.