Cover Image

Proprotein convertases in gynecological cancers /

Bibliographic Details
Main Author: Klein-Szanto, Andres J. P.
Other Authors: Bassi, Daniel, Zhang, Jirong
Format: eBook
Language:English
Published: San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan and Claypool, [2012]
Series:Colloquium digital library of life sciences.
Colloquium series on protein activation and cancer ; # 2.
Subjects:
Cancer in women.
Generative organs, Female > Cancer.
Protein precursors.
Genital Neoplasms, Female.
Proprotein Convertases.
PACE4
cancer
carcinogenesis
furin
proprotein convertases
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Acknowledgments
  • Abbreviations
  • 1. Introduction
  • 2. Expression of PCS in gynecological cancers
  • 2.1 Ovarian cancer
  • 2.2 Endometrial cancer
  • 2.3 Cervical cancer
  • 2.4 Squamous cell carcinomas of the female genital tract
  • 3. PCS and associated substrates as markers for gynecological cancers
  • 3.1 CA-125 and mesothelin
  • 4. Role of PCS in tumor progression
  • 4.1 Epithelial-mesenchymal transition in ovarian cancer
  • 4.2 Osteopontin and the regulation of furin expression in cervical cancer
  • 4.3 Membrane-type metalloproteinases and ovarian cancer invasion
  • 4.4 Semaphorin 3E and advanced ovarian cancer
  • 5. Inhibition of furin as therapeutic strategy
  • 6. Conclusions
  • References
  • Senior author biography
  • Titles of related interest.